Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study

JJ Harding, J Fan, DY Oh, HJ Choi, JW Kim… - The Lancet …, 2023 - thelancet.com
Background HER2 is overexpressed or amplified in a subset of biliary tract cancer.
Zanidatamab, a bispecific antibody targeting two distinct HER2 epitopes, exhibited …

Efficacy of endoscopic mucosal resection versus endoscopic submucosal dissection for rectal neuroendocrine tumors≤ 10mm: a systematic review and meta-analysis

C Zhou, F Zhang, Y We - Annals of Saudi Medicine, 2023 - annsaudimed.net
BACKGROUND: Endoscopic mucosal resection (EMR) and endoscopic submucosal
dissection (ESD) are surgical methods used for rectal neuroendocrine tumors (NETs) with …

[HTML][HTML] Spatiotemporal patterns of esophageal cancer burden attributable to behavioral, metabolic, and dietary risk factors from 1990 to 2019: Longitudinal …

P Li, J Jing, W Liu, J Wang, X Qi… - JMIR Public Health and …, 2023 - publichealth.jmir.org
Background Esophageal cancer (EC) is the sixth leading cause of cancer-related burden
with distinct regional variations globally. Although the burden of EC has decreased, the …

Prognostic value of PD‑L1 expression and CD68 macrophages in tumor nest of patients with primary gastric cancer

Y Zou, J Wang, J Zhang, Q Guo… - Oncology …, 2023 - spandidos-publications.com
The programmed death receptor 1/programmed death receptor ligand 1 axis (PD-1/PD-L1)
is involved in tumor immune escape and is a potential prognostic biomarker and anti-tumor …

Different trends of gastric cancer in China, Japan, Republic of Korea and United States of America

F Zhao, D Yang, Y Lan, X Li - iScience, 2024 - cell.com
Gastric cancer exerts a significant healthcare burden worldwide and is highly geographically
heterogeneous. This study investigates the burden of gastric cancer in China from 1990 to …

Secular trends and attributable risk factors of esophageal cancer deaths among non-elderly adults based on Global Burden of Disease Study

Q Li, L Zhu, T Wei, Z Zang, X Zhang, Y Wang… - Journal of Cancer …, 2023 - Springer
Objective Esophageal cancer (EC) poses a persistent threat to the health of non-elderly
adults. This study aims to elucidate the temporal trends of EC-related mortality and …

Comparison of the burden of digestive diseases between China and the United States from 1990 to 2019

J Peng, H Xu, S Huang, X Shi, P Wang… - Frontiers in Public …, 2024 - frontiersin.org
Introduction China has experienced unprecedented transformations unseen in a century
and is gradually progressing toward an emerging superpower. The epidemiological trends …

Symptom experiences and influencing factors in patients undergoing chemotherapy for gastrointestinal cancers: a qualitative study

X Huang, H Yang, Y Qiao - Frontiers in Psychology, 2024 - frontiersin.org
Objective To explore the symptom experiences and influencing factors of gastrointestinal
(GI) cancer patients on chemotherapy (CTX) in China. Methods Semi-structured interviews …

LASSO-derived prognostic model predicts cancer-specific survival in advanced pancreatic ductal adenocarcinoma over 50 years of age: a retrospective study of SEER …

Y Feng, J Yang, W Duan, Y Cai, X Liu, Y Peng - Frontiers in Oncology, 2024 - frontiersin.org
Background This study aimed to develop a prognostic model for patients with advanced
ductal adenocarcinoma aged≥ 50 years. Methods Patient information was extracted from …

Cellular communication network 1 promotes CASP2 mRNA expression but suppresses its protein translation in esophageal adenocarcinoma

R Xu, Z Jiang, X Meng, L Xing, W Aladan… - Journal of Cell …, 2024 - Wiley Online Library
Induction of apoptosis in tumor cells is one of the best ways to cure cancer. While most
apoptosis requires a chain of caspase activation, CASP2 can do this all by itself. The …