[HTML][HTML] Platelet-activating anti-PF4 disorders: an overview
TE Warkentin - Seminars in hematology, 2022 - Elsevier
Abstract Platelet factor 4 (PF4) is a highly cationic tetrameric protein that can be targeted by
platelet-activating anti-PF4 antibodies of immunoglobulin G (IgG) class. Certain features of …
platelet-activating anti-PF4 antibodies of immunoglobulin G (IgG) class. Certain features of …
Pathogenesis of heparin-induced thrombocytopenia
GM Arepally, DB Cines - Translational Research, 2020 - Elsevier
There are currently no effective substitutes for high intensity therapy with unfractionated
heparin (UFH) for cardiovascular procedures based on its rapid onset of action, ease of …
heparin (UFH) for cardiovascular procedures based on its rapid onset of action, ease of …
Hypotheses behind the very rare cases of thrombosis with thrombocytopenia syndrome after SARS-CoV-2 vaccination
As of 4 April 2021, a total of 169 cases of cerebral venous sinus thrombosis (CVST) and 53
cases of splanchnic vein thrombosis were reported to EudraVigilance among around 34 …
cases of splanchnic vein thrombosis were reported to EudraVigilance among around 34 …
A flow cytometric assay to detect platelet-activating antibodies in VITT after ChAdOx1 nCov-19 vaccination
S Handtke, M Wolff, C Zaninetti… - Blood, The Journal …, 2021 - ashpublications.org
Vaccination is crucial in combatting the severe acute respiratory syndrome coronavirus 2
pandemic. The rare complication of thrombocytopenia and thrombotic complications at …
pandemic. The rare complication of thrombocytopenia and thrombotic complications at …
Monoclonal and oligoclonal anti-platelet factor 4 antibodies mediate VITT
AJ Kanack, A Bayas, G George… - Blood, The Journal …, 2022 - ashpublications.org
Kanack and colleagues analyze anti-platelet factor 4 antibodies from 5 patients with vaccine-
induced thrombotic thrombocytopenia (VITT) secondary to COVID-19 adenoviral vaccination …
induced thrombotic thrombocytopenia (VITT) secondary to COVID-19 adenoviral vaccination …
Predictors of mortality in thrombotic thrombocytopenia after adenoviral COVID-19 vaccination: the FAPIC score
Aims The clinical manifestation and outcomes of thrombosis with thrombocytopenia
syndrome (TTS) after adenoviral COVID-19 vaccine administration are largely unknown due …
syndrome (TTS) after adenoviral COVID-19 vaccine administration are largely unknown due …
Heparin-induced thrombocytopenia is associated with a high risk of mortality in critical COVID-19 patients receiving heparin-involved treatment
X Liu, X Zhang, Y Xiao, T Gao, G Wang, Z Wang… - MedRxiv, 2020 - medrxiv.org
Background Coronavirus infectious disease 2019 (COVID-19) has developed into a global
pandemic. It is essential to investigate the clinical characteristics of COVID-19 and uncover …
pandemic. It is essential to investigate the clinical characteristics of COVID-19 and uncover …
The COVID complex: a review of platelet activation and immune complexes in COVID-19
SD Jevtic, I Nazy - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a highly prothrombotic viral infection that primarily
manifests as an acute respiratory syndrome. However, critically ill COVID-19 patients will …
manifests as an acute respiratory syndrome. However, critically ill COVID-19 patients will …
Frequency of thrombocytopenia and platelet factor 4/heparin antibodies in patients with cerebral venous sinus thrombosis prior to the COVID-19 pandemic
MS van Kammen, MR Heldner, J Brodard, A Scutelnic… - Jama, 2021 - jamanetwork.com
Importance Cases of cerebral venous sinus thrombosis in combination with
thrombocytopenia have recently been reported within 4 to 28 days of vaccination with the …
thrombocytopenia have recently been reported within 4 to 28 days of vaccination with the …
[HTML][HTML] Treatment of drug-induced immune thrombocytopenias
I Marini, G Uzun, K Jamal, T Bakchoul - Haematologica, 2022 - ncbi.nlm.nih.gov
Several therapeutic agents can cause thrombocytopenia by either immune-mediated or non-
immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct …
immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct …