Cerebral blood flow regulation by nitric oxide: recent advances

N Toda, K Ayajiki, T Okamura - Pharmacological reviews, 2009 - ASPET
Nitric oxide (NO) is undoubtedly quite an important intercellular messenger in cerebral and
peripheral hemodynamics. This molecule, formed by constitutive isomers of NO synthase …

Endothelial influences on cerebrovascular tone

J Andresen, NI Shafi… - Journal of applied …, 2006 - journals.physiology.org
The cerebrovascular endothelium exerts a profound influence on cerebral vessels and
cerebral blood flow. This review summarizes current knowledge of various dilator and …

[HTML][HTML] Molecular and cellular basis of small-and intermediate-conductance, calcium-activated potassium channel function in the brain

P Pedarzani, M Stocker - Cellular and Molecular Life Sciences, 2008 - Springer
Small conductance calcium-activated potassium (SK or K Ca 2) channels link intracellular
calcium transients to membrane potential changes. SK channel subtypes present different …

Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II

H Girouard, L Park, J Anrather, P Zhou… - … , and vascular biology, 2007 - Am Heart Assoc
Objective—Angiotensin II (AngII) disrupts the regulation of the cerebral circulation through
superoxide, a reactive oxygen species (ROS) generated by a nox2-containing NADPH …

Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling

CF Lourenço, A Ledo, RM Barbosa, J Laranjinha - Experimental neurology, 2017 - Elsevier
Nitric oxide (radical dot NO)-dependent pathways and cerebrovascular dysfunction have
been shown to contribute to the cognitive decline and neurodegeneration observed in …

Endothelium-derived hyperpolarizing factor: a cousin to nitric oxide and prostacyclin

RM Bryan, J You, EM Golding… - The Journal of the …, 2005 - pubs.asahq.org
There is now strong evidence that an endothelial mechanism, other than nitric oxide or
prostacyclin, exists for dilating arteries and arterioles. This third pathway has been named …

Endothelial coordination of cerebral vasomotion via myoendothelial gap junctions containing connexins 37 and 40

RE Haddock, TH Grayson… - American Journal …, 2006 - journals.physiology.org
Control of cerebral vasculature differs from that of systemic vessels outside the blood-brain
barrier. The hypothesis that the endothelium modulates vasomotion via direct …

[HTML][HTML] Effects of aircraft noise cessation on blood pressure, cardio-and cerebrovascular endothelial function, oxidative stress, and inflammation in an experimental …

MTB Jimenez, A Gericke, K Frenis, S Rajlic… - Science of the Total …, 2023 - Elsevier
Large epidemiological studies have shown that traffic noise promotes the development of
cardiometabolic diseases. It remains to be established how long these adverse effects of …

Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain

S Chrissobolis, B Banfi, CG Sobey… - Journal of applied …, 2012 - journals.physiology.org
Angiotensin II (Ang II) promotes vascular disease through several mechanisms including by
producing oxidative stress and endothelial dysfunction. Although multiple potential sources …

Nox2-derived superoxide contributes to cerebral vascular dysfunction in diet-induced obesity

CM Lynch, DA Kinzenbaw, X Chen, S Zhan, E Mezzetti… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Obesity is an increasing epidemic worldwide; however, little is
known about effects of obesity produced by high-fat diet (HFD) on the cerebral circulation …