Advances in the cystic fibrosis drug development pipeline

C Esposito, M Kamper, J Trentacoste, S Galvin… - Life, 2023 - mdpi.com
Cystic fibrosis is a genetic disease that results in progressive multi-organ manifestations with
predominance in the respiratory and gastrointestinal systems. The significant morbidity and …

Bacteriophages in nature: recent advances in research tools and diverse environmental and biotechnological applications

M Bisen, K Kharga, S Mehta, N Jabi… - Environmental Science and …, 2024 - Springer
Bacteriophages infect and replicate within bacteria and play a key role in the environment,
particularly in microbial ecosystems and bacterial population dynamics. The increasing …

Isolation and characterization of three Pseudomonas aeruginosa viruses with therapeutic potential

X Wang, J Tang, W Dang, Z Xie, F Zhang… - Microbiology …, 2023 - Am Soc Microbiol
As one of the most common pathogens of opportunistic and hospital-acquired infections,
Pseudomonas aeruginosa is associated with resistance to diverse antibiotics, which …

[HTML][HTML] Exploring Local Reservoirs for Bacteriophages with Therapeutic Potential against ESKAPE Pathogens

AA Loera Piedra, IL Becerra Mejía, B Luna Galicia… - Microbiology …, 2024 - mdpi.com
Bacteriophage therapy is a promising strategy used to treat antimicrobial-resistant or
persistent bacterial infections. More recently, the clinical utility of bacteriophages has been …

[HTML][HTML] Phage Therapy: An Alternative Approach to Combating Multidrug-Resistant Bacterial Infections in Cystic Fibrosis

M Cocorullo, G Stelitano, LR Chiarelli - International Journal of Molecular …, 2024 - mdpi.com
Patients with cystic fibrosis (CF) are prone to developing life-threatening lung infections with
a variety of pathogens that are difficult to eradicate, such as Burkholderia cepacia complex …

A synthetic biology approach to assemble and reboot clinically relevant Pseudomonas aeruginosa tailed phages

T Ipoutcha, R Racharaks, S Huttelmaier… - Microbiology …, 2024 - Am Soc Microbiol
The rise in the frequency of antibiotic resistance has made bacterial infections, specifically
Pseudomonas aeruginosa, a cause for greater concern. Phage therapy is a promising …

Exploring the dynamics of mixed-species biofilms involving Candida spp. and bacteria in cystic fibrosis

K Gourari-Bouzouina, Z Boucherit-Otmani… - Archives of …, 2024 - Springer
Cystic fibrosis (CF) is an inherited disease that results from mutations in the gene
responsible for the cystic fibrosis transmembrane conductance regulator (CFTR). The …

Phage Therapy: An Alternative Approach to Combat Multi-drug Resistant Infections in Cystic Fibrosis

M Cocorullo, G Stelitano, LR Chiarelli - 2024 - preprints.org
Phage Therapy: An Alternative Approach to Combat Multi-drug Resistant Infections in Cystic
Fibrosis Page 1 Review Not peer-reviewed version Phage Therapy: An Alternative Approach …

[PDF][PDF] Synthesis of green-engineered silver nanoparticles using Cymbopogon citratus (lemongrass) and its antibacterial activity against clinical Pseudomonas …

MMJ Arsene, AKL Davares, S Goriainov, PI Viktorovna… - pdfs.semanticscholar.org
Abstract Background and Aim: The use of bioengineered nanocomposites as antimicrobials
has increased in recent years, but very few investigations have been conducted to test their …