[HTML][HTML] Prevention of pregnancy loss: combining progestogen treatment and psychological support

N Tetruashvili, A Domar, A Bashiri - Journal of clinical medicine, 2023 - mdpi.com
Pregnancy loss can be defined as a loss before either 20 or 24 weeks of gestation (based
on the first day of the last menstrual period) or the loss of an embryo or fetus less than 400 g …

[HTML][HTML] Vaginal Nanoformulations for the Management of Preterm Birth

A Mir, RV Vartak, K Patel, SM Yellon, SE Reznik - Pharmaceutics, 2022 - mdpi.com
Preterm birth (PTB) is a leading cause of infant morbidity and mortality in the world. In 2020,
1 in 10 infants were born prematurely in the United States. The World Health Organization …

Cervical MUC5B and MUC5AC are barriers to ascending pathogens during pregnancy

Y Ueda, H Mogami, Y Kawamura… - The Journal of …, 2022 - academic.oup.com
Context Cervical excision is a risk factor for preterm birth. This suggests that the cervix plays
an essential role in the maintenance of pregnancy. Objective We investigated the role of the …

Autism‐like behavior of murine offspring induced by prenatal exposure to progestin is associated with gastrointestinal dysfunction due to claudin‐1 suppression

L Xiao, J Feng, W Zhang, J Pan, M Wang… - The FEBS …, 2023 - Wiley Online Library
Autism spectrum disorders (ASD) are associated with the contribution of many prenatal risk
factors; in particular, the sex hormone progestin and vitamin D receptor (VDR) are …

[HTML][HTML] Changes in cervical elastography, cervical length and endocervical canal width after cerclage for cervical insufficiency: an observational ultrasound study

MH Hsieh, CP Chen, FJ Sun, YY Chen… - BMC Pregnancy and …, 2023 - Springer
Background We previously demonstrated that pregnant women with a history of cervical
insufficiency had a softer anterior cervical lip, shorter cervical length and wider endocervical …

A pragmatic evaluation of the implementation and acceptance of a universal second trimester cervical length screening program in an un-selected population

S Reddy, Z Haidar, C Downing, J Sonek… - Archives of Gynecology …, 2024 - Springer
Purpose To evaluate patients' acceptance of a universal transvaginal ultrasound cervical
length (CL) screening program and the feasibility of initiating treatment with progesterone in …

Exposure to Progestin 17-OHPC Induces Gastrointestinal Dysfunction through Claudin 1 Suppression in Female Mice with Increased Anxiety-Like Behaviors

L Zeng, X Zhang, Q Shen, L He, X Liu, X Zeng… - …, 2024 - karger.com
Introduction: Progestin, commonly used in oral contraception and preventing preterm birth,
elicits various offtarget side effects on brain and gastrointestinal (GI) functions, yet the …

A Single Administration of Progesterone during the Neonatal Period Shows No Structural Changes in Male Reproductive Tracts in Mice

T Omotehara, H Nakata, K Nagahori… - Acta Histochemica et …, 2023 - jstage.jst.go.jp
The concentration of female-dominant steroid hormones, such as progesterone and
estrogen, drops after birth in neonates. We have reported that neonatal estrogen treatment …

Adjuvant Treatment with Oral Dydrogesterone in the Prevention of Preterm Labor: A Randomized, Double-Blinded, Placebo-Controlled Trial

H Keshtmandi, M Mirmohammadkhani… - Reproductive …, 2023 - Springer
We conducted a double-blind, randomized, placebo-controlled clinical trial to evaluate the
efficacy of oral dydrogesterone (DG) on maternal and neonatal consequences in the …

[PDF][PDF] Vaginal Nanoformulations for the Management of Preterm Birth.

A Mir, RV Vartak, K Patel, SM Yellon, SE Reznik - Pharmaceutics, 2022 - researchgate.net
Preterm birth (PTB) is a leading cause of infant morbidity and mortality in the world. In 2020,
1 in 10 infants were born prematurely in the United States. The World Health Organization …