[HTML][HTML] Understanding Clinical Effectiveness and Safety Implications of Botulinum Toxin in Children: A Narrative Review of the Literature
S Crisafulli, F Ciccimarra, Z Khan, F Maccarrone… - Toxins, 2024 - mdpi.com
Since its first approval by the Food and Drug Administration in 1989 for strabismus,
botulinum toxin indications of use have been widely expanded. Due to its anticholinergic …
botulinum toxin indications of use have been widely expanded. Due to its anticholinergic …
[HTML][HTML] The Role of Botulinum Toxin Type-A in Spasticity: Research Trends from a Bibliometric Analysis
Botulinum toxin type-A (BoNT-A) has emerged as a key therapeutic agent for the
management of spasticity. This paper presents a comprehensive bibliometric and visual …
management of spasticity. This paper presents a comprehensive bibliometric and visual …
[HTML][HTML] Safety and efficacy of repeat long-term incobotulinumtoxinA treatment for lower limb or combined upper/lower limb spasticity in children with cerebral palsy
P Kaňovský, F Heinen, AS Schroeder… - Journal of pediatric …, 2022 - content.iospress.com
PURPOSE: The open-label phase 3 “Treatment with IncobotulinumtoxinA in Movement
Open-Label”(TIMO) study investigated longer-term safety and efficacy of …
Open-Label”(TIMO) study investigated longer-term safety and efficacy of …
[HTML][HTML] Botox injection in treatment of sialorrhea in children with cerebral palsy
M Ghazavi, S Rezaii, M Ghasemi, N Azin… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: The occurrence of sialorrhea (drooling) in children with cerebral palsy is one of
the important complications of this disease, which is associated with the impaired quality of …
the important complications of this disease, which is associated with the impaired quality of …
Botulinum toxin for motor disorders
D Safarpour, B Jabbari - Handbook of Clinical Neurology, 2023 - Elsevier
Botulinum neurotoxins are a group of biological toxins produced by the gram-negative
bacteria Clostridium botulinum. After intramuscular injection, they produce dose-related …
bacteria Clostridium botulinum. After intramuscular injection, they produce dose-related …
[HTML][HTML] Spasticity-related pain in children/adolescents with cerebral palsy. Part 1: Prevalence and clinical characteristics from a pooled analysis
F Heinen, M Bonfert, P Kaňovský… - Journal of pediatric …, 2022 - content.iospress.com
PURPOSE: A large prospective database from three Phase 3 studies allowed the study of
spasticity-related pain (SRP) in pediatric cerebral palsy (CP). METHODS: Baseline …
spasticity-related pain (SRP) in pediatric cerebral palsy (CP). METHODS: Baseline …
[HTML][HTML] Safety profile and lack of immunogenicity of incobotulinumtoxinA in pediatric spasticity and sialorrhea: A pooled analysis
S Berweck, M Banach, D Gaebler-Spira, HG Chambers… - Toxins, 2022 - mdpi.com
IncobotulinumtoxinA, a pure botulinumtoxinA formulation, is free of accessory proteins. This
analysis provides pooled safety data from phase 3 trials of children/adolescents (2–17 …
analysis provides pooled safety data from phase 3 trials of children/adolescents (2–17 …
Safety and effectiveness of thermal radiofrequency applied to the musculocutaneous nerve for patients with spasticity
S Otero-Villaverde, J Formigo-Couceiro… - Frontiers in …, 2024 - frontiersin.org
Objective Evaluate safety and effectiveness of thermal radiofrequency in the
musculocutaneous nerve in patients with focal elbow flexor spasticity. Design Ambispective …
musculocutaneous nerve in patients with focal elbow flexor spasticity. Design Ambispective …
[HTML][HTML] IncobotulinumtoxinA Injection for Treating Children with Idiopathic Toe Walking: A Retrospective Efficacy and Safety Study
M Filippetti, A Picelli, R Di Censo, S Vantin… - Toxins, 2022 - mdpi.com
There is no gold-standard treatment for idiopathic toe walking (ITW). Some previous
evidence suggested that botulinum neurotoxin-A injection might improve ITW. This is a …
evidence suggested that botulinum neurotoxin-A injection might improve ITW. This is a …
[HTML][HTML] Spasticity-related pain in children/adolescents with cerebral palsy. Part 2: IncobotulinumtoxinA efficacy results from a pooled analysis
M Bonfert, F Heinen, P Kaňovský… - Journal of pediatric …, 2023 - content.iospress.com
PURPOSE: This pooled analysis of data from three Phase 3 studies investigated the effects
of incobotulinumtoxinA on spasticity-related pain (SRP) in children/adolescents with uni …
of incobotulinumtoxinA on spasticity-related pain (SRP) in children/adolescents with uni …