European Association of Urology guidelines on testicular cancer: 2023 update

A Patrikidou, W Cazzaniga, D Berney, J Boormans… - European Urology, 2023 - Elsevier
Abstract Context Each year the European Association of Urology (EAU) produce a document
based on the most recent evidence on the diagnosis, therapy, and follow-up of testicular …

miRNAs orchestration of testicular germ cell tumors–Particular emphasis on diagnosis, progression and drug resistance

AE Elesawy, AI Abulsoud, HAM Moustafa… - … -Research and Practice, 2023 - Elsevier
Testicular cancer (TC) is one of the most frequently incident solid tumors in males. A growing
prevalence has been documented in developed countries. Although recent advances have …

[HTML][HTML] Testicular seminoma and non-seminoma: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up☆

J Oldenburg, DM Berney, C Bokemeyer… - Annals of …, 2022 - annalsofoncology.org
Germ-cell tumours (GCTs) affect predominantly younger males aged between 15 and 40
years, with nearly 74 500 new cases estimated globally in 2020. 1 About one-third of all GCT …

[HTML][HTML] Detection of recurrence through microRNA-371a-3p serum levels in a follow-up of stage I testicular germ cell tumors in the DRKS-00019223 study

G Belge, C Dumlupinar, T Nestler, M Klemke… - Clinical Cancer …, 2024 - AACR
Purpose: Surveillance of clinical stage I (CSI) testicular germ cell tumors (GCT) is hampered
by low sensitivity and specificity of current biomarkers for detecting relapses. This study …

[HTML][HTML] Male infertility and the risk of developing testicular cancer: a critical contemporary literature review

G Maiolino, E Fernández-Pascual, MA Ochoa Arvizo… - Medicina, 2023 - mdpi.com
Background and Objectives: The relationship between male infertility (MI) and testicular
cancer (TC) is bilateral. On one hand, it is well-established that patients diagnosed with TC …

Molecular biomarkers with potential clinical application in testicular cancer

J Lobo, AM Acosta, GJ Netto - Modern Pathology, 2023 - Elsevier
Testicular germ cell tumors (TGCTs) and sex cord-stromal tumors (SCSTs) are the most
common testicular neoplasms. The morphological spectrum of such tumors is wide, with …

[HTML][HTML] DigiMir test: establishing a novel pipeline for MiR-371a quantification using droplet digital PCR in liquid biopsies from testicular germ cell tumor patients

JP Sequeira, J Lobo, V Constâncio… - Frontiers in …, 2022 - frontiersin.org
Testicular germ cell tumors (TGCTs) are the most common cancers in young-adult male
patients aged between 15 and 39 years. Hsa-miR-371a-3p is currently the most reliable …

Prognostic factors for relapse in patients with clinical stage I testicular seminoma: a nationwide, population-based cohort study

T Wagner, BG Toft, J Lauritsen, M Bandak… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Approximately 20% of patients with clinical stage I seminoma relapse. Tumor
size and rete testis invasion have been identified as risk factors for relapse. However, the …

[HTML][HTML] Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium

A Fonseca, J Lobo, FK Hazard, J Gell… - British journal of …, 2022 - nature.com
Germ cell tumours (GCTs) are a heterogeneous group of rare neoplasms that present in
different anatomical sites and across a wide spectrum of patient ages from birth through to …

[HTML][HTML] Circulating microRNAs as diagnostic biomarkers for melanoma: a systematic review and meta-analysis

N Wu, H Sun, Q Sun, F Zhang, L Ma, Y Hu, X Cong - BMC cancer, 2023 - Springer
Background Recent studies have shown that circulating microRNAs (miRNAs) can be used
as diagnostic biomarkers for melanoma. This study aimed to evaluate the diagnostic value of …