Background Pediatric disorders include a range of highly penetrant, genetically
heterogeneous conditions amenable to genomewide diagnostic approaches. Finding a …

Autism spectrum disorders (ASD) are complex conditions that stem from a combination of
genetic, epigenetic and environmental influences during early pre-and postnatal childhood …

As prenatal exposure to certain older antiseizure medications (ASMs) has been linked with
poorer neurodevelopmental outcomes in children, the use of newer ASMs throughout …

Importance Women with epilepsy frequently need antiseizure medication (ASM) to prevent
seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to …

Background Maternal use of valproate during pregnancy has been associated with an
increased risk of neurodevelopmental disorders in children. Although most studies of other …

Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

Introduction Status epilepticus (SE) in pregnancy represents a life-threatening medical
emergency for both mother and fetus. Pregnancy-related pharmacokinetic modifications and …

Background and Objectives To undertake a systematic review of the available literature to
examine the relationship between prenatal antiseizure medication (ASM) exposure and …

Mental disorders including depression and anxiety are continuously rising their prevalence
across the globe. Early-life experience of individuals emerges as a main risk factor …

Importance Cancer is a leading cause of death among children worldwide. Treatments used
for medically assisted reproduction (MAR) are suspected risk factors because of their …