[HTML][HTML] Efficient, cell-based simulations of cardiac electrophysiology; The Kirchhoff Network Model (KNM)

KH Jæger, A Tveito - NPJ systems biology and applications, 2023 - nature.com
Mathematical models based on homogenized representation of cardiac tissue have greatly
improved our understanding of cardiac electrophysiology. However, these models are too …

[HTML][HTML] Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac …

KH Jæger, KG Hustad, X Cai, A Tveito - Frontiers in Physics, 2021 - frontiersin.org
The EMI model represents excitable cells in a more accurate manner than traditional
homogenized models at the price of increased computational complexity. The increased …

[HTML][HTML] An explicit local space-time adaptive framework for monodomain models in cardiac electrophysiology

D Ogiermann, D Balzani, LE Perotti - Computer Methods in Applied …, 2024 - Elsevier
We present a new explicit local space–time adaptive framework to decrease the time
required for monodomain simulations for cardiac electrophysiology. Based on the localized …

Physiological accuracy in simulating refractory cardiac tissue: the volume-averaged bidomain model vs. the cell-based EMI model

J Reimer, SA Domínguez-Rivera, J Sundnes… - arXiv preprint arXiv …, 2023 - arxiv.org
The refractory period of cardiac tissue can be quantitatively described using strength-interval
(SI) curves. The information captured in SI curves is pertinent to the design of anti-arrhythmic …

A simulation-based method to study the LQT1 syndrome remotely using the EMI model

S Domínguez, J Reimer, KR Green… - Emerging Technologies …, 2021 - Springer
The COVID-19 pandemic has spurred the development and application of new technologies
in telemedicine to overcome limitations on in-person interactions between patients and …

[HTML][HTML] Second-order Rosenbrock-exponential (ROSEXP) methods for partitioned differential equations

V Dallerit, T Buvoli, M Tokman, S Gaudreault - Numerical Algorithms, 2024 - Springer
In this paper, we introduce a new framework for deriving partitioned implicit-exponential
integrators for stiff systems of ordinary differential equations and construct several time …

Gating-enhanced IMEX splitting methods for cardiac monodomain simulation

KR Green, RJ Spiteri - Numerical Algorithms, 2019 - Springer
The electrical activity in excitable cardiac tissue can be simulated using the so-called
monodomain model. The monodomain model is a continuum-based multi-scale model that …

Stabilized hybrid discontinuous Galerkin finite element method for the cardiac monodomain equation

BM Rocha, RW Dos Santos, I Igreja… - … journal for numerical …, 2020 - Wiley Online Library
Numerical methods for solving the cardiac electrophysiology model, which describes the
electrical activity in the heart, are proposed. The model problem consists of a nonlinear …

[图书][B] Speeding up high-order algorithms in computational fluid and kinetic dynamics: Based on characteristics tracing and low-rank structures

J Nakao - 2023 - search.proquest.com
Many physical phenomena can be described by nonlinear partial differential equations
(PDEs). Yet, analytic solutions are oftentimes unavailable, and lab experiments can be time …

Negative time splitting is stable

D Li, C Quan - arXiv preprint arXiv:2107.07332, 2021 - arxiv.org
For high order (than two) in time operator-splitting methods applied to dissipative systems, a
folklore issue is the appearance of negative-time/backward-in-time linear evolution …