[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

[PDF][PDF] Epidemiology of worldwide spinal cord injury: a literature review

Y Kang, H Ding, H Zhou, Z Wei, L Liu… - J …, 2018 - pdfs.semanticscholar.org
Study design: A literature review of worldwide epidemiology of spinal cord injury (SCI).
Objectives: To review the epidemiological indicators of SCI, such as incidence, prevalence …

Time is spine: a review of translational advances in spinal cord injury: JNSPG 75th Anniversary Invited Review Article

JH Badhiwala, CS Ahuja, MG Fehlings - Journal of Neurosurgery: Spine, 2018 - thejns.org
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical,
emotional, and economic consequences for patients, families, and society at large. Timely …

[HTML][HTML] Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling …

Y Wang, X Lai, D Wu, B Liu, N Wang… - Stem cell research & …, 2021 - Springer
Background Although exosomes, as byproducts of human umbilical cord mesenchymal stem
cells (hUC-MSCs), have been demonstrated to be an effective therapy for traumatic spinal …

Oxidative stress following spinal cord injury: From molecular mechanisms to therapeutic targets

M Yu, Z Wang, D Wang, M Aierxi, Z Ma… - Journal of …, 2023 - Wiley Online Library
Spinal cord injury (SCI) is a medical condition that results from severe trauma to the central
nervous system; it imposes great psychological and economic burdens on affected patients …

[HTML][HTML] Clinical trials of stem cell treatment for spinal cord injury

K Yamazaki, M Kawabori, T Seki, K Houkin - International Journal of …, 2020 - mdpi.com
There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …

[HTML][HTML] Neuropathic pain after spinal cord injury: challenges and research perspectives

R Shiao, CA Lee-Kubli - Neurotherapeutics, 2018 - Elsevier
Neuropathic pain is a debilitating consequence of spinal cord injury (SCI) that remains
difficult to treat because underlying mechanisms are not yet fully understood. In part, this is …

[HTML][HTML] Incidence of traumatic spinal cord injury worldwide: a systematic review, data integration, and update

SB Jazayeri, SF Maroufi, E Mohammadi… - World neurosurgery …, 2023 - Elsevier
Objectives This review was designed to update our earlier systematic review which
evaluated both published and unpublished evidence on the incidence of traumatic spinal …

The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2 …

JF Talbott, WD Whetstone, WJ Readdy… - Journal of neurosurgery …, 2015 - thejns.org
OBJECT Previous studies that have evaluated the prognostic value of abnormal changes in
signals on T2-weighted MRI scans of an injured spinal cord have focused on the …

Falls after spinal cord injury: a systematic review and meta-analysis of incidence proportion and contributing factors

A Khan, C Pujol, M Laylor, N Unic, M Pakosh, J Dawe… - Spinal Cord, 2019 - nature.com
Introduction Falls are detrimental to the well-being of individuals with spinal cord injury
(SCI). To establish effective fall prevention initiatives, a comprehensive understanding of …