Thyroid hormones are important during development of the mammalian brain, acting on
migration and differentiation of neural cells, synaptogenesis, and myelination. The actions of …

Heterotrimeric G protein–coupled receptors (GPCRs) are found on the surface of all cells of
multicellular organisms and are major mediators of intercellular communication. More than …

Identification of AD (Alzheimer's disease)-related genes obtained from blood samples is
crucial for early AD diagnosis. We used three public datasets, ADNI, AddNeuroMed1 …

We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

Mood disorders (depression, bipolar disorders) are prevalent and disabling. They are also
highly co-morbid with other psychiatric disorders. Currently there are no objective measures …

Introduction Profiling the spatial-temporal expression pattern and characterizing the
regulatory networks of brain tissues are vital for understanding the pathophysiology of …

Recent genome-wide association studies (GWAS) have identified DNA sequence variations
that exhibit unequivocal statistical associations with many common chronic diseases …

Suicides are a leading cause of death in psychiatric patients, and in society at large.
Developing more quantitative and objective ways (biomarkers) for predicting and tracking …

Gene expression studies bridge the gap between DNA information and trait information by
dissecting biochemical pathways into intermediate components between genotype and …

Bipolar affective disorder (BPAD) is suspected to arise in part from malfunctions of the
circadian system, a system that enables adaptation to a daily and seasonally cycling …