[HTML][HTML] Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology
S Sato - Journal of physiological anthropology, 2021 - Springer
Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
Evolution by gene loss
R Albalat, C Cañestro - Nature Reviews Genetics, 2016 - nature.com
The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
[HTML][HTML] The African genome variation project shapes medical genetics in Africa
Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …
detailed characterization of African genetic diversity is needed. The African Genome …
Settling the score: variant prioritization and Mendelian disease
When investigating Mendelian disease using exome or genome sequencing, distinguishing
disease-causing genetic variants from the multitude of candidate variants is a complex …
disease-causing genetic variants from the multitude of candidate variants is a complex …
The α-thalassemias
FB Piel, DJ Weatherall - New England Journal of Medicine, 2014 - Mass Medical Soc
The α-Thalassemias | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
On the evolution of lactase persistence in humans
Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …
frequency across human populations. This trait represents an adaptation to the …
[HTML][HTML] G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map
RE Howes, FB Piel, AP Patil, OA Nyangiri… - PLoS …, 2012 - journals.plos.org
Background Primaquine is a key drug for malaria elimination. In addition to being the only
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …
[HTML][HTML] Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax
DE Loy, W Liu, Y Li, GH Learn, LJ Plenderleith… - International journal for …, 2017 - Elsevier
Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …
malaria infections, and thus pose a serious public health challenge. To control and …
[图书][B] Human evolutionary genetics: origins, peoples and disease
M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …
together molecular genetics and genomics to the study of the origins and movements of …
[HTML][HTML] Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature communications, 2019 - nature.com
The human genetic factors that affect resistance to infectious disease are poorly understood.
Here we report a genome-wide association study in 17,000 severe malaria cases and …
Here we report a genome-wide association study in 17,000 severe malaria cases and …