Food-drug interactions can be associated with alterations in the pharmacokinetic and
pharmacodynamic profile of various drugs that may have clinical implications. The various …

The use of oral anticancer drugs has shown a steady increase. Most patients prefer
anticancer oral therapy to intravenous treatment primarily for the convenience of a home …

Pharmacokinetic interactions between food and orally administered drugs involve changes
mainly in the absorption and metabolism of a drug, and may have clinical implications. Such …

Traditionally, anticancer therapy has been dominated by intravenous drug therapy.
However, oral agents provide an attractive approach to chemotherapy and use of oral …

Purpose: Desmoid-type fibromatosis (DF) are locally aggressive neoplasms, with a need for
effective systemic treatment in case of progression to avoid the short-and long-term …

Background Oral (po) chemotherapy treatments gained increasing importance in the
palliative treatment of metastatic breast cancer (MBC). Aim of this survey was to evaluate the …

In the past years, alternative administration routes and pharmaceutical formulations of
anticancer agents have been investigated in order to improve conventional chemotherapy …

With the recent growth in oral anticancer agents (OAA), pharmacists working in the
community have recognised the urgent need to develop safe and effective systems to …

Phase I trials are a critical first step in the study of novel cancer therapeutic approaches.
Their primary goals are to identify the recommended dose, schedule and pharmacologic …

The effects of food on the pharmacokinetics and safety profile of a soft-gel capsule
formulation of vinorelbine (Navelbine Oral) were evaluated in fed and fasted patients with …