Heat shock proteins (HSPs) constitute a large family of molecular chaperones classified by
their molecular weights, and they include HSP27, HSP40, HSP60, HSP70, and HSP90 …

Kidney disease can be either acute kidney injury (AKI) or chronic kidney disease (CKD) and
it can lead to the development of functional organ failure. Mesenchymal stem cells (MSCs) …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …

MSCs show promise in protecting against IRI-induced damage. They appear to help
recovery mainly by affecting the levels of inflammation and apoptosis during the organ repair …

Background Studies have shown that the Klotho gene has tremendous potential for future
therapeutic purposes in both acute and chronic kidney diseases (CKD). This study aimed to …

Acute kidney injury (AKI) represents a worldwide public health issue of increasing incidence,
with a significant morbi-mortality. AKI treatment mostly relies on supportive manoeuvres in …

Cisplatin has been hypothesized to induce nephrotoxicity through triggering the apoptosis of
tubular cells; however, the drug remains widely administered for the treatment of tumors …

Chronic kidney disease (CKD) is caused by hypoxia in the renal tissue, leading to
inflammation and increased migration of pathogenic cells. Studies showed that leukocytes …

Chronic kidney disease (CKD) affects 1 in 10 members of the general population, placing
these patients at an increasingly high risk of kidney failure. Despite the significant burden of …

Background Acute hypoxic proximal tubule (PT) injury and subsequent maladaptive repair
present high mortality and increased risk of acute kidney injury (AKI)-chronic kidney disease …