Glycoconjugates: synthesis, functional studies, and therapeutic developments

SS Shivatare, VS Shivatare, CH Wong - Chemical reviews, 2022 - ACS Publications
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Plant-derived antimicrobial peptides as potential antiviral agents in systemic viral infections

N Mammari, Y Krier, Q Albert, M Devocelle… - Pharmaceuticals, 2021 - mdpi.com
Numerous studies have led to a better understanding of the mechanisms of action of viruses
in systemic infections for the development of prevention strategies and very promising …

The evolutionary dynamics of endemic human coronaviruses

WK Jo, C Drosten, JF Drexler - Virus Evolution, 2021 - academic.oup.com
Community protective immunity can affect RNA virus evolution by selecting for new antigenic
variants on the scale of years, exemplified by the need of annual evaluation of influenza …

Single and multiple dose pharmacokinetics and safety of ZSP1273, an RNA polymerase PB2 protein inhibitor of the influenza A virus: a phase 1 double-blind study in …

Y Hu, H Li, M Wu, H Zhang, Y Ding… - Expert Opinion on …, 2021 - Taylor & Francis
Background Influenza is an acute respiratory illness. Treating with antiviral drugs can
decrease the duration of illness and serious complications. ZSP1273 is a small-molecule …

Whole-genome sequencing reveals origin and evolution of influenza A (H1N1) pdm09 viruses in Lincang, China, from 2014 to 2018

XN Zhao, HJ Zhang, D Li, JN Zhou, YY Chen, YH Sun… - PloS one, 2020 - journals.plos.org
The continuous variation of the seasonal influenza viruses, particularly A (H1N1) pdm09,
persistently threatens human life and health around the world. In local areas of southwest …

A systematic review of influenza epidemiology and surveillance in the Eastern Mediterranean and North African Region

S Soudani, A Mafi, Z Al Mayahi, S Al Balushi… - Infectious Diseases and …, 2022 - Springer
Seasonal influenza represents a huge health burden, resulting in significant mortality and
morbidity. Following the 2009 H1N1 pandemic, focus has been directed on the burden of …

Molecular detection of influenza A and B viruses in four consecutive influenza seasons 2015–16 to 2018–19 in a tertiary center in Western Saudi Arabia

A Althaqafi, F Farahat, A Alsaedi, M Alshamrani… - Journal of epidemiology …, 2021 - Springer
Introduction Influenza infection poses a significant public health threat. The core for disease
prevention and control relies on strengthened surveillance activities, particularly in Saudi …

A comprehensive molecular and epidemiological characterization of influenza viruses circulating 2016–2020 in North Macedonia

M Kuzmanovska, G Boshevska, E Janchevska… - Frontiers in …, 2021 - frontiersin.org
Influenza viruses know no boundaries, representing an example of rapid virus evolution
combined with pressure exerted by the host's immune system. Seasonal influenza causes 4 …

Evaluation of the added value of viral genomic information for predicting severity of influenza infection

N Van Goethem, A Robert, N Bossuyt… - BMC infectious …, 2021 - Springer
Background The severity of an influenza infection is influenced by both host and viral
characteristics. This study aims to assess the relevance of viral genomic data for the …

Evolution of Indian influenza A (H1N1) hemagglutinin strains: A comparative analysis of the pandemic Californian HA strain

SS Pushan, M Samantaray, M Rajagopalan… - Frontiers in Molecular …, 2023 - frontiersin.org
The need for a vaccine/inhibitor design has become inevitable concerning the emerging
epidemic and pandemic viral infections, and the recent outbreak of the influenza A (H1N1) …