Human islet amyloid polypeptide (hIAPP) is widely studied due to its close correlation with
the pathogenic mechanism of type II diabetes mellitus (T2DM). Bioflavonoids have been …

Therapeutic nanoparticles can be combined with different anticancer drugs to achieve a
synergistic therapy and avoid the limitations of traditional medicine and thus have clinical …

A major hallmark of Alzheimer's disease is the cerebral accumulation and resulting
cytotoxicity of amyloid-β peptides, particularly Aβ42. In this study, we used an MTT assay to …

A signature feature of age-related neurodegenerative proteinopathies is the misfolding and
aggregation of proteins, typically amyloid-β (Aβ) in Alzheimer's disease (AD) and α …

The first synthetic strategy for nonsymmetrical 3, 3 ″-biflavones is described. To this end, a
novel visible-light iridium-catalyzed radical C-3 alkylation of flavones with o-methoxy …

Protein aggregation and amyloid fibrillation can lead to several serious human diseases and
protein drug ineffectiveness. The complexity and dynamics of protein folding present unique …

Cognitive enhancers (nootropics) are drugs to treat cognition deficits in patients suffering
from Alzheimer's disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or …

Alzheimer's disease is one of the neurodegenerative diseases which causes cognition
deficit. There are currently few medications available to treat Alzheimer's disease, even …

Alzheimer's disease (AD) is characterized by progressive memory loss due to extracellular
senile plaques and intracellular neurofibrillary tangles. The toxic β-amyloid (Aβ) aggregates …

Amyloid β (Aβ) aggregation plays an essential role in promoting the progression of
Alzheimer's disease (AD). Therefore, the inhibition of Aβ aggregation is a potential …