Sympathetic nervous system (SNS) hyperactivity is mediated by elevated catecholamine
(CA) secretion from the adrenal medulla, as well as enhanced norepinephrine (NE) release …

Aims: Heart failure (HF) is associated with profound changes in cardiac metabolism. At
present, there is still a lack of relevant research to explore the key microbiome and their …

Potential health benefits of an acute fast include reductions in blood pressure and increases
in vagal cardiac control. These purported health benefits could put fasted humans at risk for …

Ketones are alternative energy substrates for the heart and kidney but no studies have
investigated their metabolism simultaneously in both organs in humans. The present double …

Myocardial infarction (MI) is a life-threatening cardiovascular disease that, on average,
results in 8.5 million deaths worldwide each year. Timely revascularization of occluded …

BHB offers potential therapeutic advantages in the comprehensive approach to improve
outcomes for TBI patients. However, careful consideration of safety and efficacy is essential …

Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent and now
accounts for half of all heart failure cases. This rise is largely attributed to growing rates of …

The prevalence of cardiovascular diseases (CVDs) is a growing global health concern.
Recent advances have demonstrated significant reductions in acute cardiovascular events …

Ketone bodies, consisting of beta-hydroxybutyrate, acetoacetate, and acetone, are
metabolic byproducts known as energy substrates during fasting. Recent advancements …

The digital health field is experiencing substantial growth due to its potential for sustained
and longitudinal deployment. In turn, this may drive improved monitoring and intervention as …