Tumor-draining lymph nodes: At the crossroads of metastasis and immunity

H du Bois, TA Heim, AW Lund - Science immunology, 2021 - science.org
Early engagement of the lymphatic system by solid tumors in peripheral, nonlymphoid
tissues is a clinical hallmark of cancer and often forecasts poor prognosis. The significance …

A systematic review and meta-analysis of prophylactic central neck dissection on short-term locoregional recurrence in papillary thyroid carcinoma after total …

BHH Lang, SH Ng, LLH Lau, BJ Cowling, KP Wong… - Thyroid, 2013 - liebertpub.com
Background: Prophylactic central neck dissection (pCND) at the time of total thyroidectomy
(TT) remains controversial in clinically node-negative (cN0) papillary thyroid carcinoma …

Reprogramming of sentinel lymph node microenvironment during tumor metastasis

YL Li, WC Hung - Journal of biomedical science, 2022 - Springer
Metastasis is a major cause of death in patients with cancer. The two main routes for cancer
cell dissemination are the blood and lymphatic systems. The underlying mechanism of …

Outcomes for patients with papillary thyroid cancer who do not undergo prophylactic central neck dissection

IJ Nixon, LY Wang, I Ganly, SG Patel… - Journal of British …, 2016 - academic.oup.com
Background The role of prophylactic central neck dissection (CND) in the management of
papillary thyroid cancer (PTC) is controversial. This report describes outcomes of an …

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy

A Garrahy, MS Murphy, P Sheahan - Head & neck, 2016 - Wiley Online Library
Background Postoperative hypocalcemia is a common complication of thyroidectomy.
Magnesium is known to modulate serum calcium levels and hypomagnesemia may impede …

Is systematic identification of all four parathyroid glands necessary during total thyroidectomy?: a prospective study

P Sheahan, R Mehanna, N Basheeth… - The …, 2013 - Wiley Online Library
Objectives/Hypothesis Routine identification of all four parathyroid glands has been
advocated as a means of reducing rates of postoperative hypocalcemia and inadvertent …

Severe vitamin D deficiency: a significant predictor of early hypocalcemia after total thyroidectomy

T Al-Khatib, AM Althubaiti, A Althubaiti… - … –Head and Neck …, 2015 - journals.sagepub.com
Objective To assess the role of preoperative serum 25 hydroxyvitamin D as predictor of
hypocalcemia after total thyroidectomy. Study Design Retrospective cohort study. Setting …

[HTML][HTML] Lymph node metastasis and tumor-educated immune tolerance: Potential therapeutic targets against distant metastasis

JM Peng, YL Su - Biochemical Pharmacology, 2023 - Elsevier
Lymph node metastasis has been shown to positively associated with the prognosis of many
cancers. However, in clinical treatment, lymphadenectomy is not always successful …

Vitamin D and risk of postoperative hypocalcemia after total thyroidectomy

TP Griffin, MS Murphy, P Sheahan - JAMA Otolaryngology–Head …, 2014 - jamanetwork.com
Importance Transient hypocalcemia is a well-recognized occurrence after total
thyroidectomy. It has been hypothesized that underlying vitamin D deficiency may increase …

Observation of clinically negative central compartment lymph nodes in papillary thyroid carcinoma

IJ Nixon, I Ganly, SG Patel, LG Morris, FL Palmer… - Surgery, 2013 - Elsevier
Background The role of prophylactic central neck dissection in the management of papillary
thyroid cancer (PTC) is controversial. We report our experience of an observational …