Advances in structural-guided modifications of siRNA

Q Li, M Dong, P Chen - Bioorganic & Medicinal Chemistry, 2024 - Elsevier
To date, the US Food and Drug Administration (FDA) has approved six small interfering RNA
(siRNA) drugs: patisiran, givosiran, lumasiran, inclisiran, vutrisiran, and nedosiran, serving …

Enhancing or Quenching of a Mitochondria-Targeted AIEgens-Floxuridine Sensor by the Regulation of pH-Dependent Self-assembly, Efficient Recognition of Hg2+ …

Y Zeng, Z Wang, L Zeng, H Xiong - Analytical Chemistry, 2023 - ACS Publications
Biocompatible fluorescent probes have emerged as essential tools in life sciences for
visualizing subcellular structures and detecting specific analytes. Herein, we report the …

Novel Dioxane-and Morpholino Nucleotide Analogues with Improved Off-Target Profiles in siRNAs

AF Stepan, D Rankic, FH Lutter - Synfacts, 2023 - thieme-connect.com
Novel Dioxane- and Morpholino Nucleotide Analogues with Improved Off-Target Profiles in
siRNAs Page 1 © 2023. Thieme. All rights reserved. Georg Thieme Verlag KG …