Renal acid–base homeostasis is a complex process, effectuated by bicarbonate
reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular …

Research in the last decade has revolutionized the way in which we view mitochondria.
Mitochondria are no longer viewed solely as cellular powerhouses; rather, mitochondria are …

Abstract pH has been considered one of the paramount factors in bodily functions because
most cellular tasks exclusively rely on precise pH values. In this context, the current …

Diabetic nephropathy and cardiomyopathy are two major causes of mortality among patients
with diabetes mellitus (DM). Since current diabetic medications are associated with various …

Owing to their ability to breach the skin in a minimally invasive manner, microneedles (MNs)
have seen increased interest for potential diagnostic applications. This is particularly true of …

The allosteric regulation of pyruvate kinase M2 (PKM2) affects the switching of the PKM2
protein between the high-activity and low-activity states that allow ATP and lactate …

Abstract Background Acidosis in severe Plasmodium falciparum malaria is associated with
high mortality, yet the pathogenesis remains incompletely understood. The aim of this study …

This review summarizes the newly discovered molecular mechanism of secretin‐stimulated
urine HCO3–excretion and the role of cystic fibrosis transmembrane conductance regulator …

Acidosis is a common feature of many neuronal diseases and often accompanied with
adverse consequences such as pain and neuronal injury. Before the discovery of acid …

Sodium Bicarbonate in Different Critically Ill Conditions: From Physiology to Clinical Practice |
Anesthesiology | American Society of Anesthesiologists Skip to Main Content Advertisement …