[PDF][PDF] A threshold selection method from gray-level histograms

N Otsu - Automatica, 1975 - dspace.tul.cz
Summary 16S rRNA-targeted oligonucleotide probes for eubacteria (EUB338), ammonium-
oxidizing bacteria (Nsm156) and nitrite-oxidizing bacteria (Nb1000) were used for the rapid …

An overview on target-based drug design against kinetoplastid protozoan infections: Human African trypanosomiasis, Chagas disease and leishmaniases

V Kourbeli, E Chontzopoulou, K Moschovou, D Pavlos… - Molecules, 2021 - mdpi.com
The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …

Can cysteine protease cross-class inhibitors achieve selectivity?

L Cianni, CW Feldmann, E Gilberg… - Journal of medicinal …, 2019 - ACS Publications
Cysteine proteases are important targets for the discovery of novel therapeutics for many
human diseases. From parasitic diseases to cancer, cysteine proteases follow a common …

Heteroleptic Oxidovanadium(V) Complexes with Activity against Infective and Non-Infective Stages of Trypanosoma cruzi

G Scalese, I Machado, G Salinas, L Pérez-Díaz… - Molecules, 2021 - mdpi.com
Five heteroleptic compounds,[VVO (IN-2H)(LH)], where L are 8-hydroxyquinoline derivatives
and IN is a Schiff base ligand, were synthesized and characterized in both the solid and …

The cytotoxic and anti-leishmanial activity of Oregano (Origanum vulgare) essential oil: An in vitro, in vivo, and in silico study

F Tomiotto-Pellissier, BT da Silva Bortoleti… - Industrial Crops and …, 2022 - Elsevier
This study was aimed at investigating the leishmanicidal and immunomodulatory of oregano
essential oil (OEO) from Origanum vulgare on experimental Leishmania amazonensis …

Melittin as a promising anti-protozoan peptide: current knowledge and future prospects

H Memariani, M Memariani - Amb Express, 2021 - Springer
Protozoan diseases such as malaria, leishmaniasis, Chagas disease, and sleeping sickness
still levy a heavy toll on human lives. Deplorably, only few classes of anti-protozoan drugs …

Redox Balance Keepers and Possible Cell Functions Managed by Redox Homeostasis in Trypanosoma cruzi

AC Mesías, NJ Garg, MP Zago - Frontiers in Cellular and Infection …, 2019 - frontiersin.org
The toxicity of oxygen and nitrogen reactive species appears to be merely the tip of the
iceberg in the world of redox homeostasis. Now, oxidative stress can be seen as a two-sided …

[HTML][HTML] Sesquiterpenoids and flavonoids from Inula viscosa induce programmed cell death in kinetoplastids

I Zeouk, I Sifaoui, A López-Arencibia… - Biomedicine & …, 2020 - Elsevier
Neglected tropical diseases such as leishmaniasis and American trypanosomiasis represent
an increasing health problem. Current treatments are not satisfactory which remains an …

New multifunctional Ru (II) organometallic compounds show activity against Trypanosoma brucei and Leishmania infantum

F Rivas, C Del Mármol, G Scalese, L Pérez-Díaz… - Journal of Inorganic …, 2022 - Elsevier
Human African trypanosomiasis (sleeping sickness) and leishmaniasis are prevalent
zoonotic diseases caused by genomically related trypanosomatid protozoan parasites …

Leishmanicidal Activity of Guanidine Derivatives against Leishmania infantum

FS Almeida, VP Moreira, ES Silva, LL Cardoso… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a neglected tropical infectious disease with thousands of cases annually; it
is of great concern to global health, particularly the most severe form, visceral leishmaniasis …