[HTML][HTML] Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Functions and therapeutic interventions of non-coding RNAs associated with TLR signaling pathway in atherosclerosis

R Margiana, F Alsaikhan, GRL Al-Awsi, I Patra… - Cellular …, 2022 - Elsevier
Nowadays, emerging data demonstrate that the toll-like receptor (TLR) signaling pathway
plays an important role in the progression of inflammatory atherosclerosis. Indeed …

[HTML][HTML] Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88 …

V Quagliariello, M Passariello, A Di Mauro… - Frontiers in …, 2022 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) have significantly changed the oncology
clinic in recent years, improving survival expectations in cancer patients. ICI therapy have a …

T-cell MyD88 is a novel regulator of cardiac fibrosis through modulation of T-cell activation

AL Bayer, S Smolgovsky, N Ngwenyama… - Circulation …, 2023 - Am Heart Assoc
BACKGROUND: Cardiac inflammation in heart failure is characterized by the presence of
damage-associated molecular patterns, myeloid cells, and T cells. Cardiac damage …

Repair of the infarcted heart: cellular effectors, molecular mechanisms and therapeutic opportunities

I Hilgendorf, S Frantz, NG Frangogiannis - Circulation Research, 2024 - Am Heart Assoc
The adult mammalian heart has limited endogenous regenerative capacity and heals
through the activation of inflammatory and fibrogenic cascades that ultimately result in the …

[HTML][HTML] Burdock fructooligosaccharide ameliorates the hypercholesterolemia and vascular inflammation in mice by regulating cholesterol homeostasis and anti …

Y Meng, Q Ma, X Xu, L Feng, Q Chen, Y Chen… - Journal of Functional …, 2023 - Elsevier
Burdock fructooligosaccharide (BFO) is a type of linear inulin extracted from burdock root. In
this study, we studied the effect of BFO in hypercholesterolemic mice model and found that …

The role of immune system in atherosclerosis: Molecular mechanisms, controversies, and future possibilities

T Zhang, C Pang, M Xu, Q Zhao, Z Hu, X Jiang… - Human Immunology, 2024 - Elsevier
Numerous cardiovascular disorders have atherosclerosis as their pathological
underpinning. Numerous studies have demonstrated that, with the aid of pattern recognition …

[HTML][HTML] Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome

AI Pranty, W Wruck, J Adjaye - Cells, 2023 - mdpi.com
Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs
as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin …

Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation

Y He, W Tian, M Zhang, H Qiu, H Li, X Shi… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Jieduquyuziyin prescription (JP), as a traditional Chinese
medicine formula, is extensively applied to treat systemic lupus erythematosus (SLE). Its …

Study on finishing inner wall of CoCr alloy cardiovascular stent tube via novel atomized CBN/metal spherical magnetic abrasive powders

Z Song, Y Zhao, G Liu, C Cao, Y Gao, X Zhang… - Journal of Manufacturing …, 2023 - Elsevier
In this study, in order to solve the problem that the inner wall of the cardiovascular stent is
difficult to polish, the magnetic abrasive finishing (MAF) method is used to finish the inner …