Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

Reactive oxygen species (ROS) are necessary for normal cell signaling and the
antimicrobial defense of the skin. However excess production of ROS can disrupt the cellular …

Leaning from nature and taking advantage of nature is a one of important way in scientific
research. In this work, as natural clay mineral, montmorillonite (Mt) was used to synthesize …

Abstract MITOL/MARCH5 is an E3 ubiquitin ligase that plays a crucial role in the control of
mitochondrial quality and function. However, the significance of MITOL in cardiomyocytes …

Renal proximal tubular cells are highly vulnerable to different types of assaults during
filtration and reabsorption, leading to acute renal dysfunction and eventual chronic kidney …

Background With the development of nanotechnology, various nanomaterials with enzyme-
like activity (nanozymes) have been reported. Due to their superior properties, nanozymes …

The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …

Visualization and quantification of important biomolecules like glutathione (GSH) in live cells
are highly important. The existing methods are mostly from optical detection and lack of …

The human retina, which is part of the central nervous system, has exceptionally high energy
demands that requires an efficient metabolism of glucose, lipids, and amino acids …

Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …