Oleacein attenuates lipopolysaccharide-induced inflammation in THP-1-derived macrophages by the inhibition of TLR4/MyD88/NF-κB pathway

S Cirmi, A Maugeri, C Russo, L Musumeci… - International Journal of …, 2022 - mdpi.com
It is known that plant phenolic compounds exert anti-inflammatory activity through both anti-
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …

Platinum‐based TREM2 inhibitor suppresses tumors by remodeling the immunosuppressive microenvironment

T Yang, S Zhang, H Yuan, Y Wang… - Angewandte Chemie …, 2023 - Wiley Online Library
Triggering receptor expressed on myeloid cells‐2 (TREM2) is a key pro‐tumorigenic marker
of tumor‐infiltrating macrophages, showing potent immunosuppressive activity in tumor …

Novel long non-coding RNAs associated with inflammation and macrophage activation in human

A Chini, P Guha, VS Malladi, Z Guo, SS Mandal - Scientific Reports, 2023 - nature.com
Inflammation plays a central role in immune response and macrophage activation. Emerging
studies demonstrate that along with proteins and genomic factors, noncoding RNA are …

Concurrent suppression of Aβ aggregation and NLRP3 inflammasome activation for treating Alzheimer's disease

T Yang, L Zhang, Y Shang, Z Zhu, S Jin, Z Guo… - Chemical …, 2022 - pubs.rsc.org
Alzheimer's disease (AD) is a neurodegenerative illness accompanied by severe memory
loss, cognitive disorders and impaired behavioral ability. Amyloid β-peptide (Aβ) …

Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA

T Liu, T Huang, J Li, A Li, C Li, X Huang, D Li, S Wang… - PLoS …, 2023 - journals.plos.org
THP-1 monocyte, which can be differentiated into macrophages by PMA, is widely used in
researches on pathogen infection and host innate immunity, but reports on the induction …

Placental Hofbauer cell polarization resists inflammatory cues in vitro

C Schliefsteiner, S Ibesich, C Wadsack - International Journal of …, 2020 - mdpi.com
Feto-placental Hofbauer cells (HBCs) are macrophages residing in placental stroma. They
are generally described as anti-inflammatory M2 polarized cells, promoting tolerance and …

Insights into the biomechanical properties of plasma treated 3D printed PCL scaffolds decorated with gold nanoparticles

B Joseph, N Ninan, RM Visalakshan, C Denoual… - … Science and Technology, 2021 - Elsevier
Tissue engineered constructs having desired biomimetic and mechanical properties
emerged due to the complexities involved in conventional skin grafting. They facilitate tissue …

Inhalable chitosan microparticles for simultaneous delivery of isoniazid and rifabutin in lung tuberculosis treatment

L Cunha, S Rodrigues, AMR da Costa… - Drug development …, 2019 - Taylor & Francis
The direct delivery of antibiotics to the lung has been considered an effective approach to
treat pulmonary tuberculosis, which represents approximately 80% of total cases. In this …

[HTML][HTML] Convective drying of feijoa (Acca sellowiana Berg): A study on bioactivity, quality, and drying parameters

AM Castro, LE Díaz, MX Quintanilla-Carvajal… - LWT, 2023 - Elsevier
The impact of feijoa convective drying on the physicochemical characteristics, polyphenol
content, antioxidant capacity, and anti-inflammatory activity, as well as the drying parameters …

Reactive oxygen species imaging in U937 cells

A Prasad, M Sedlářová, A Balukova, A Ovsii… - Frontiers in …, 2020 - frontiersin.org
The U937 cell culture is a pro-monocytic, human histiocytic lymphoma cell line. These
monocytes can differentiate into either macrophages or dendritic cells (antigen-presenting …