[HTML][HTML] Leaky gut model of the human intestinal mucosa for testing siRNA-based nanomedicine targeting JAK1

O Hartwig, B Loretz, A Nougarede, D Jary… - Journal of Controlled …, 2022 - Elsevier
Complex in vitro models of human immune cells and intestinal mucosa may have a
translation-assisting role in the assessment of anti-inflammatory compounds. Chronic …

[HTML][HTML] Deoxynivalenol increases pro-inflammatory cytokine secretion and reduces primary bile acid transport in an inflamed intestinal in vitro co-culture model

J Wang, W Bakker, L de Haan… - Food Research …, 2023 - Elsevier
The fungal secondary metabolite deoxynivalenol (DON) that can contaminate cereal-based
food products not only induces inflammation but also reduces bile acid absorption by a …

Oat-derived β-glucans induced trained immunity through metabolic reprogramming

W Pan, S Hao, M Zheng, D Lin, P Jiang, J Zhao, H Shi… - Inflammation, 2020 - Springer
Trained immunity has been recently identified in innate immune cells, which undergo long-
term epigenetic and metabolic reprogramming after exposure to pathogens for protection …

[HTML][HTML] Silver nanoparticles affect the inflammatory response in a lung epithelial cell line

A Fehaid, R Fujii, T Sato… - The Open …, 2020 - openbiotechnologyjournal.com
Methods: We induced an inflammatory response in a lung epithelial cell line using tumor
necrosis factor-α (TNFα) as an in vitro inflammatory model. Then the effect of AgNPs on the …

Protein adsorption on surfaces functionalized with COOH groups promotes anti-inflammatory macrophage responses

E Buck, S Lee, LS Stone, M Cerruti - ACS Applied Materials & …, 2021 - ACS Publications
Implants can induce a foreign body reaction that leads to chronic inflammation and fibrosis
in the surrounding tissue. Macrophages help detect the foreign material, play a role in the …

(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway

C Wu, F Li, X Zhang, W Xu, Y Wang, Y Yao… - Frontiers in …, 2022 - frontiersin.org
Background: Gouty arthritis is a common and complex inflammatory disease that will reduce
the life quality of human beings (−)-Epicatechin (EC) is famous for antioxidant and anti …

Development and characterization of a prototypic pan-amyloid clearing agent–a novel murine peptide-immunoglobulin fusion

JS Foster, M Balachandran, TJ Hancock… - Frontiers in …, 2023 - frontiersin.org
Introduction Systemic amyloidosis is a progressive disorder characterized by the
extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and …

Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway

HY Ling, Z Yang, PJ Wang, Y Sun, SG Ju, J Li… - Chemico-Biological …, 2022 - Elsevier
Growing evidence shows that cancer progression links with both heterogeneity of the tumor
microenvironment and dysregulated activity of immune cells. Cancer-secreted exosomes …

Immune Targeting of Mycobacteria through Cell Surface Glycan Engineering

P Dzigba, AK Rylski, IJ Angera, N Banahene… - ACS Chemical …, 2023 - ACS Publications
Mycobacteria and other organisms in the order Mycobacteriales cause a range of significant
human diseases, including tuberculosis, leprosy, diphtheria, Buruli ulcer, and non …

Gallic and butyric acids modulated NLRP3 inflammasome markers in a co-culture model of intestinal inflammation

I Luzardo-Ocampo, G Loarca-Piña… - Food and chemical …, 2020 - Elsevier
Bioactive compounds from food products made from natural ingredients such as corn and
common bean could target the NLRP3 inflammasome, protein scaffolds with a key role in the …