Illuminating dendritic function with computational models

P Poirazi, A Papoutsi - Nature reviews neuroscience, 2020 - nature.com
Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …

Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Single-cell RNA sequencing uncovers a neuron-like macrophage subset associated with cancer pain

PCT Tang, JYF Chung, J Liao, MKK Chan… - Science …, 2022 - science.org
Tumor innervation is a common phenomenon with unknown mechanism. Here, we
discovered a direct mechanism of tumor-associated macrophage (TAM) for promoting de …

Function and regulation of CREB family transcription factors in the nervous system

BE Lonze, DD Ginty - Neuron, 2002 - cell.com
CREB and its close relatives are now widely accepted as prototypical stimulus-inducible
transcription factors. In many cell types, these factors function as effector molecules that …

Branching out: mechanisms of dendritic arborization

YN Jan, LY Jan - Nature Reviews Neuroscience, 2010 - nature.com
Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …

Neuronal activity–regulated gene transcription in synapse development and cognitive function

AE West, ME Greenberg - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Activity-dependent plasticity of vertebrate neurons allows the brain to respond to its
environment. During brain development, both spontaneous and sensory-driven neural …

Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system

SW Flavell, ME Greenberg - Annu. Rev. Neurosci., 2008 - annualreviews.org
Sensory experience and the resulting synaptic activity within the brain are critical for the
proper development of neural circuits. Experience-driven synaptic activity causes membrane …

From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function

PL Greer, ME Greenberg - Neuron, 2008 - cell.com
One of the unique characteristics of higher organisms is their ability to learn and adapt to
changes in their environment. This plasticity is largely a result of the brain's ability to convert …

Electrical activity in early neuronal development

NC Spitzer - Nature, 2006 - nature.com
The construction of the brain during embryonic development was thought to be largely
independent of its electrical activity. In this view, proliferation, migration and differentiation of …

Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications

DW Brann, K Dhandapani, C Wakade, VB Mahesh… - Steroids, 2007 - Elsevier
Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …