Endoplasmic stress response, the unfolded protein response (UPR), is a homeostatic
signaling pathway comprising transmembrane sensors that get activated upon alterations in …

Cadmium (Cd) is one of the most toxic environmental pollutants. Quercetin (Que) is a kind of
natural flavonoid with neuroprotective, antioxidant, and free-radical scavenging …

Background Central post-stroke pain (CPSP) is a chronic and intolerable neuropathic pain
syndrome following a cerebral vascular insult, which negatively impacts the quality of life of …

Abstract Editor's Perspective What We Already Know about This Topic The mechanisms
supporting bone cancer pain are incompletely understood Stress of the endoplasmic …

Pain is a complex and multifaceted experience. Recent research has increasingly focused
on the role of endoplasmic reticulum (ER) stress in the induction and modulation of pain …

Background Neuroinflammation, which ultimately leads to neuronal loss, is considered to
play a crucial role in numerous neurodegenerative diseases. The neuroinflammatory …

Damage to alveolar epithelial cells (AECs) caused by long-term inhalation of large amounts
of silica dust plays a significant role in the pathology of silicosis. The present study was …

Studies demonstrated that spinal autophagy was impaired in spinal nerve ligation (SNL)
rats. However, the relationship of endoplasmic reticulum (ER) stress and ER-phagy and …

Vasculitic peripheral neuropathy (VPN) arises from an inflammatory obstruction in the blood
vessels supplying peripheral nerves and subsequent ischaemic insults, which exhibits the …

Simple Summary Chronic inflammatory diseases could impact central nervous system
homeostasis, being oxidative damage of the dorsal horn, a relevant mechanism mediating …