Polyunsaturated fatty acids (PUFAs) contain≥ 2 double‐bond desaturations within the acyl
chain. Omega‐3 (n‐3) and Omega‐6 (n‐6) PUFAs are the two known important families in …

Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …

Tumor acidosis promotes disease progression through a stimulation of fatty acid (FA)
metabolism in cancer cells. Instead of blocking the use of FAs by acidic cancer cells, we …

Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

In this study, exosomes used to encapsulate curcumin (Exo-cur) or a signal transducer and
activator of transcription 3 (Stat3) inhibitor, ie, JSI124 (Exo-JSI124) were delivered …

Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Cancer is the second leading cause of death in the United States. Despite the estimated
565,650 deaths in 2008 of Americans as a result of cancer, it is mostly a preventable …

Botanical and nutritional compounds have been used for the treatment of cancer throughout
history. These compounds also may be useful in the prevention of cancer. Population …

The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …