Nucleic acid architectonics for pH-responsive DNA systems and devices

MN Mattath, D Ghosh, S Pratihar, S Shi… - ACS …, 2022 - ACS Publications
Nucleic acid-based architectures have opened up numerous opportunities for basic and
applied research in the field of DNA nanotechnology. The scheme of molecular …

Multifunctional architectures of cyclic dipeptide copolymers and composites, and modulation of multifaceted amyloid-β toxicity

H Moorthy, LP Datta, S Samanta… - ACS Applied Materials …, 2022 - ACS Publications
Alzheimer's disease (AD) is a major neurodegenerative disorder primarily characterized by
the β-amyloid (Aβ42) misfolding and aggregation-associated multifaceted amyloid toxicity …

Two-Dimensional Molecular Architectonics through Controlled Noncovalent Interactions: Structure, Functional Properties, and Applications

S Dinda, M Konar, T Govindaraju - Chemistry of Materials, 2024 - ACS Publications
Fabrication of well-defined two-dimensional (2D) architectures employing organic or organic–
inorganic hybrid molecular systems through bottom-up methodologies is a challenging task …

Cooperative dissolution of peptidomimetic vesicles and amyloid β fibrils

S Dinda, D Ghosh, T Govindaraju - Nanoscale, 2024 - pubs.rsc.org
The aggregation of amyloid proteins in the brain is a significant neurotoxic event that
contributes to neurodegenerative disorders. The aggregation of amyloid beta (Aβ) …

Differential copper-guided architectures of amyloid β peptidomimetics modulate oxidation states and catalysis

D Ghosh, M Konar, T Mondal, T Govindaraju - Nanoscale Advances, 2022 - pubs.rsc.org
Orchestration of differential architectures of designer peptidomimetics that modulate metal
oxidation states to perform multiple chemical transformations remains a challenge. Cu …

Biphasic modulation of tau liquid–liquid phase separation by polyphenols

H Moorthy, N Kamala, M Ramesh… - Chemical …, 2024 - pubs.rsc.org
Molecular tools that modulate tau liquid–liquid phase separation (LLPS) promise to treat
tauopathies. We screened a set of polyphenols and demonstrated concentration-dependent …

Effect of tetracycline hydrochloride application on dental pulp stem cell metabolism–booster or obstacle for tissue engineering?

W Wang, J Sun, G Aarabi, U Peters, F Fischer… - Frontiers in …, 2023 - frontiersin.org
Introduction: Stem cells and scaffolds are an important foundation and starting point for
tissue engineering. Human dental pulp stem cells (DPSC) are mesenchymal stem cells with …

Peptide core containing polymer–polyoxometalate hybrid as novel antifungal agent

S Biswas, L Priya Datta, T Kumar Das - Journal of Molecular and …, 2022 - World Scientific
Engineering the molecular assembly at biomolecular interface is one of the prevailing
techniques in synthetic biology to derive novel supramolecular structures. In this study, we …

Molecular architectonics

M Konar, T Govindaraju - Molecular Architectonics and Nanoarchitectonics, 2022 - Springer
Nature is full of sophisticated structures and functions orchestrated through balanced
noncovalent interactions driven by molecular assemblies. Fabrication of artificial mimics is …

Molecular Assembly of Cyclic Dipeptide: Structure to Function

D Ghosh, T Govindaraju - Peptide Self‐Assembly and …, 2024 - Wiley Online Library
The scheme of molecular architectonics allows the design and construction of diverse
molecular, nano‐, micro‐, and hierarchical architectures with a wide range of applications …