Sepsis, a heterogeneous clinical syndrome, features a systemic inflammatory response to
tissue injury or infection, followed by a state of reduced immune responsiveness …

主对感染反应失调而导致的危及生命的器官功能障碍. 依据Sepsis3. 0 诊断标准,
我国每年新发脓毒症病例约250 万例, 每年约70 万例脓毒症患者死亡, 病死率较以往增加11.4 …

Intensive care unit (ICU)-acquired infection is a common cause of poor prognosis of sepsis
in ICU. However, sepsis-associated ICU-acquired infections have not been fully …

Secondary infection in patients with sepsis triggers a new wave of inflammatory response,
which aggravates organ injury and increases mortality. Trained immunity boosts a potent …

Background: Sepsis is a leading cause of mortality in patients with neutropenia; however,
data on whether neutropenic sepsis is associated with distinct clinical characteristics and …

Background Sepsis is characterized by highly heterogeneous immune responses
associated with a spectrum of disease severity. Methods that rapidly and sensitively profile …

S. aureus and A. baumannii are among the main bacterial species responsible for several
infections worldwide due to the different resistance and virulence mechanisms, which can …

BACKGROUND The dynamic monitoring of immune status is crucial to the precise and
individualized treatment of sepsis. In this study, we aim to introduce a model to describe and …

Background Sepsis is a life-threatening condition characterized by an aberrant host
response to infection, resulting in multi-organ dysfunction. The application of currently …

Sepsis is a common complication following infections, burns, trauma, and major operations
and has become the main cause of death in non-coronary intensive care units. It was the …