The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress
which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a …

The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …

Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …

Inflammatory bowel disease (IBD) is a non-communicable disease characterized by a
chronic inflammatory process of the gut and categorized into Crohn's disease and ulcerative …

Cisplatin [cis-diamminedichloroplatinum II] is an extensively prescribed drug in cancer
chemotherapy; it is also useful for the treatment of diverse types of malignancies …

Endometrial cancer represents one of the most common gynecological tumors in the world.
Advanced and relapsed patients rely on drug therapy. Therefore, it is extremely important to …

Chronic liver diseases (CLDs) are correlated with oxidative stress induced by the
accumulation of intracellular reactive oxygen species (ROS). In this study, we employed …

Objective To explore the effects of Esculetin on liver cancer and explore potential
mechanisms of Esculetin-inducing cells death. Methods Esculetin's effects on the …

Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …