Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

PL Meroni, MO Borghi, C Grossi… - Nature Reviews …, 2018 - nature.com
Recurrent thrombosis and miscarriages are the main clinical manifestations of
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …

Discovery and characterization of 2 novel subpopulations of aPS/PT antibodies in patients at high risk of thrombosis

M Chinnaraj, W Planer, V Pengo, N Pozzi - Blood Advances, 2019 - ashpublications.org
Abstract Anti-phosphatidylserine/prothrombin (aPS/PT) antibodies are often detected in
patients with antiphospholipid syndrome (APS), but how aPS/PT engage prothrombin at the …

Anti-phospholipid antibody prevalence and association with subclinical atherosclerosis and atherothrombosis in the general population

C Selmi, M De Santis, PM Battezzati, E Generali… - International journal of …, 2020 - Elsevier
Background There is no agreement on the prevalence of anti-phospholipid antibodies
(aPLs) and the correlation with atherosclerosis and cardiovascular (CV) events in the …

The clinical value of assays detecting antibodies against domain I of β2-glycoprotein I in the antiphospholipid syndrome

D Yin, B de Laat, KMJ Devreese, H Kelchtermans - Autoimmunity reviews, 2018 - Elsevier
As the clinical symptoms of the antiphospholipid syndrome (APS) frequently occur
irrespective of the syndrome, diagnosis predominantly depends on the laboratory assays …

Interference of DOACs in different DRVVT assays for diagnosis of lupus anticoagulants

T Flieder, M Weiser, TH Eller, M Dittrich… - Thrombosis …, 2018 - Elsevier
Objective Determination of lupus anticoagulants (LA) is an important, but still challenging
test in the diagnosis of antiphospholipid syndrome (APS). This is especially the case in …

[HTML][HTML] Influence of anticardiolipin and anti‐β2 glycoprotein I antibody cutoff values on antiphospholipid syndrome classification

L Vanoverschelde, H Kelchtermans, J Musial… - Research and practice …, 2019 - Elsevier
Background Anticardiolipin (aCL) and anti‐β2 glycoprotein I (aβ2GPI) immunoglobulin (Ig)
G/IgM antibodies are 2 of the 3 laboratory criteria for classification of antiphospholipid …

Laboratory diagnostics of antiphospholipid syndrome

V Pengo, E Bison, G Denas, SP Jose… - … in thrombosis and …, 2018 - thieme-connect.com
Diagnosis of antiphospholipid syndrome (APS) lies in the recognition of antiphospholipid
antibodies (aPL). As standardization of tests for the detection of aPL is far from being optimal …

Classification of primary antiphospholipid syndrome as systemic lupus erythematosus: analysis of a cohort of 214 patients

R Paule, N Morel, V Le Guern, M Fredi, L Coutte… - Autoimmunity …, 2018 - Elsevier
Objectives To assess the limitations of the SLICC (Systemic Lupus International
Collaborating Clinics) classification criteria for systemic lupus erythematosus (SLE), in …

Antiphospholipid syndrome

S Sciascia, M Radin, K Schreiber - The Rose and Mackay Textbook of …, 2024 - Elsevier
Antiphospholipid syndrome (APS) was first identified as a distinct syndrome in the early
1980s in patients suffering from lupus with antiphospholipid antibodies (aPL), repeated …