Recently, clinical trial results have established inhibitors of B‐cell receptor (BCR)‐
associated kinase (BAKi), with or without CD20 moniclonal antibodies (mAbs), as the …

B-cell linker protein (BLNK) is an adaptor protein that plays a crucial role in the B cell
antigen receptor (BCR) signal pathway. To investigate the function of BLNK in teleost fish …

Background: Impaired B-cell receptor (BCR) function has been associated with the progress
of several B-cell malignancies. The spleen tyrosine kinase (SYK) represents a potential …

Protein kinases are fundamental within almost all cellular signal transduction networks.
Among these, Bruton's tyrosine kinase (Btk), which belongs to the Tec family of proteins …

The identification of a Btk mutation in a male patient with< 2% CD19+ B cells warrants
making the diagnosis of X-linked Agammaglobulinemia (XLA). Herein we report the case of …

This study aimed to investigate the clinicopathological and prognostic impact of B-cell linker
(BLNK) protein expression in colorectal cancer (CRC) as its function in CRC remains …

Bruton's tyrosine kinase (BTK) is a Tec-family tyrosine kinase and plays a crucial role in B
cell antigen receptor (BCR) signal pathway. Mutations in humans and mice BTK gene …

Intracellular expression of Ab fragments has been efficiently used to inactivate therapeutic
targets, oncogene products, and to induce viral resistance in plants. Ab fragments expressed …

Bruton's tyrosine kinase (Btk) is essential for BCR signal transduction and has diverse
functions in B cells. Although Btk has been extensively studied, the role of lysine acetylation …

Surface Ig (sIg) expression is a critical checkpoint during avian B cell development. Only
cells that express sIg colonize bursal follicles, clonally expand, and undergo Ig …