Biogenesis, architecture, and function of bacterial type IV secretion systems

PJ Christie, K Atmakuri, V Krishnamoorthy… - Annu. Rev …, 2005 - annualreviews.org
Abstract Type IV secretion (T4S) systems are ancestrally related to bacterial conjugation
machines. These systems assemble as a translocation channel, and often also as a surface …

The structural biology of type IV secretion systems

R Fronzes, PJ Christie, G Waksman - Nature Reviews Microbiology, 2009 - nature.com
Type IV secretion systems (T4SSs) are versatile secretion systems that are found in both
Gram-negative and Gram-positive bacteria and secrete a wide range of substrates, from …

Bacterial conjugation: a two‐step mechanism for DNA transport

M Llosa, FX Gomis‐Rüth, M Coll… - Molecular …, 2002 - Wiley Online Library
Bacterial conjugation is a promiscuous DNA transport mechanism. Conjugative plasmids
transfer themselves between most bacteria, thus being one of the main causal agents of the …

The transfer of DNA from Agrobacterium tumefaciens into plants: a feast of fundamental insights

J Zupan, TR Muth, O Draper, P Zambryski - The plant journal, 2000 - Wiley Online Library
This review is dedicated to Jeff Schell, one of the founders of modernAgrobiology', the
genetic and molecular dissection of crown gall disease. Together with notable scientists at …

Structure of a type IV secretion system core complex

R Fronzes, E Schafer, L Wang, HR Saibil, EV Orlova… - science, 2009 - science.org
Type IV secretion systems (T4SSs) are important virulence factors used by Gram-negative
bacterial pathogens to inject effectors into host cells or to spread plasmids harboring …

Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines

PJ Christie - Molecular microbiology, 2001 - Wiley Online Library
Bacterial conjugation systems are highly promiscuous macromolecular transfer systems that
impact human health significantly. In clinical settings, conjugation is exceptionally …

[HTML][HTML] Type IV secretion: the Agrobacterium VirB/D4 and related conjugation systems

PJ Christie - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2004 - Elsevier
The translocation of DNA across biological membranes is an essential process for many
living organisms. In bacteria, type IV secretion systems (T4SS) are used to deliver DNA as …

The mating pair formation system of conjugative plasmids—a versatile secretion machinery for transfer of proteins and DNA

G Schröder, E Lanka - Plasmid, 2005 - Elsevier
The mating pair formation (Mpf) system functions as a secretion machinery for intercellular
DNA transfer during bacterial conjugation. The components of the Mpf system, comprising a …

A Homologue of an Operon Required for DNA Transfer in Agrobacterium Is Required in Brucella abortusfor Virulence and Intracellular Multiplication

R Sieira, DJ Comerci, DO Sánchez… - Journal of …, 2000 - Am Soc Microbiol
As part of a Brucella abortus 2308 genome project carried out in our laboratory, we
identified, cloned, and sequenced a genomic DNA fragment containing a locus (virB) highly …

Protein secretion and the pathogenesis of bacterial infections

VT Lee, O Schneewind - Genes & development, 2001 - genesdev.cshlp.org
The skin, the oral cavity, and the gastrointestinal tract of humans are colonized with bacteria.
Microbial entry into the blood or blood-circulated tissues is hindered by anatomical barriers …