[HTML][HTML] Biliary epithelial senescence in liver disease: there will be SASP

V Meadows, L Baiocchi, D Kundu, K Sato… - Frontiers in Molecular …, 2021 - frontiersin.org
Cellular senescence is a pathophysiological phenomenon in which proliferative cells enter
cell cycle arrest following DNA damage and other stress signals. Natural, permanent DNA …

Advances in understanding of biliary atresia pathogenesis and progression–a riddle wrapped in a mystery inside an enigma

M Davenport, R Kronfli, E Makin - Expert Review of …, 2023 - Taylor & Francis
Introduction Biliary atresia is a potentially fatal condition of the bile ducts–both intra-and
extrahepatic, for which we have no cure. Though principally a cholestatic condition, much of …

Predicting native liver injury and survival in biliary atresia

M Hukkinen, M Pihlajoki, MP Pakarinen - Seminars in Pediatric Surgery, 2020 - Elsevier
Several patient and treatment related factors significantly modify outcomes of biliary atresia.
The extremely variable prognosis mandates intensive postoperative monitoring following …

[HTML][HTML] Current understanding in the clinical characteristics and molecular mechanisms in different subtypes of biliary atresia

L He, PHY Chung, VCH Lui, CSM Tang… - International Journal of …, 2022 - mdpi.com
Biliary atresia is a severe obliterative cholangiopathy in early infancy that is by far the most
common cause of surgical jaundice and the most common indicator for liver transplantation …

[HTML][HTML] Identification of liver immune microenvironment-related hub genes in liver of biliary atresia

J Zhang, Y Luo, M Feng, Q Xia - Frontiers in Pediatrics, 2022 - frontiersin.org
Background: Biliary atresia (BA) is one of the most common and fatal abnormalities of
newborns. Increasing evidences indicated that immunology was the critical part of the …

[HTML][HTML] Liver secretin receptor predicts portoenterostomy outcomes and liver injury in biliary atresia

N Godbole, I Nyholm, M Hukkinen, JR Davidson… - Scientific Reports, 2022 - nature.com
Biliary atresia (BA) is a chronic neonatal cholangiopathy characterized by fibroinflammatory
bile duct damage. Reliable biomarkers for predicting native liver survival (NLS) following …

mRNA and lncRNA expression profiles of liver tissues in children with biliary atresia

W Wu, W Wu, Y Ye, T Li… - Experimental and …, 2022 - spandidos-publications.com
Progressive liver fibrosis is the most common phenotype in biliary atresia (BA). A number of
pathways contribute to the fibrosis process so comprehensive understanding the …

Developmental histology of the portal plate in biliary atresia: observations and implications

E La Pergola, Y Zen, M Davenport - Pediatric Surgery International, 2021 - Springer
Purpose The key characteristic of biliary atresia (BA) is obliteration of the extrahepatic bile
ducts at the level of the porta hepatis. We aimed to relate the immunohistochemical features …

Biliary atresia

P Ramachandran - Liver, Gall Bladder, and Bile Ducts, 2023 - books.google.com
Biliary atresia (BA) is a progressive obstructive cholangiopathy which affects the biliary tract
in infants causing cholestasis and ultimately cirrhosis. If left untreated, it is fatal, leading to …

[HTML][HTML] Biomarkers in Biliary Atresia Following Successful Portoenterostomy Surgery

N Godbole - 2023 - helda.helsinki.fi
Biliary atresia (BA) is a rare pediatric liver disease characterized by fibrotic, inflammatory
and obliterative damage of the bile ducts and obstruction of the bile flow. Untreated …