Opioid craving does not incubate over time in inpatient or outpatient treatment studies: Is the preclinical incubation of craving model lost in translation?
Within addiction science, incubation of craving is an operational label used to describe time-
dependent increases in drug seeking during periods of drug deprivation. The purpose of this …
dependent increases in drug seeking during periods of drug deprivation. The purpose of this …
Neuroplasticity-related genes correlate with individual differences in distinct phases of oxycodone self-administration in male rats
FM Vassoler, KE Budge, SB Isgate, KR Gildawie… - …, 2024 - Elsevier
Opioid use disorder (OUD) is a chronic condition associated with long-lasting molecular and
behavioral changes. Animals with prolonged access to opioids develop behaviors similar to …
behavioral changes. Animals with prolonged access to opioids develop behaviors similar to …
The impact of heroin self-administration and environmental enrichment on ventral tegmental CRF1 receptor expression
E Galaj, ED Barrera, K Persaud… - International Journal …, 2023 - academic.oup.com
Background There is a strong link between chronic stress and vulnerability to drug abuse
and addiction. Corticotropin releasing factor (CRF) is central to the stress response that …
and addiction. Corticotropin releasing factor (CRF) is central to the stress response that …
Environmental Enrichment during Abstinence Reduces Oxycodone Seeking and c-Fos Expression in a Subpopulation of Medial Prefrontal Cortex Neurons
B Glaeser, V Panariello, A Banerjee… - Drug and Alcohol …, 2024 - Elsevier
Background Several preclinical studies have demonstrated that environmental enrichment
(EE) during abstinence reduces drug seeking for psychostimulant and opioid drugs. Drug …
(EE) during abstinence reduces drug seeking for psychostimulant and opioid drugs. Drug …