Zebrafish as an emerging model for studying complex brain disorders

AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond

AV Kalueff, M Gebhardt, AM Stewart, JM Cachat… - Zebrafish, 2013 - liebertpub.com
Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

AJ Filiano, Y Xu, NJ Tustison, RL Marsh, W Baker… - Nature, 2016 - nature.com
Immune dysfunction is commonly associated with several neurological and mental
disorders. Although the mechanisms by which peripheral immunity may influence neuronal …

Measuring behavioral and endocrine responses to novelty stress in adult zebrafish

J Cachat, A Stewart, L Grossman, S Gaikwad, F Kadri… - Nature protocols, 2010 - nature.com
Several behavioral assays are currently used for high-throughput neurophenotyping and
screening of genetic mutations and psychotropic drugs in zebrafish (Danio rerio). In this …

[HTML][HTML] Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

Measuring anxiety in zebrafish: a critical review

C Maximino, TM de Brito, AW da Silva Batista… - Behavioural brain …, 2010 - Elsevier
Zebrafish are increasingly being used in behavioral neuroscience,
neuropsychopharmacology and neurotoxicology. Recently, behavioral screens used to …

Zebrafish (Danio rerio): A newcomer with great promise in behavioral neuroscience

R Gerlai - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Behavioral neuroscience is an interdisciplinary field aimed at understanding the
neurobiology of behavior. Numerous investigators turn to animals to model and understand …

Modeling anxiety using adult zebrafish: a conceptual review

A Stewart, S Gaikwad, E Kyzar, J Green, A Roth… - …, 2012 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as a useful animal model in neurobehavioral
research. Mounting evidence shows the suitability of zebrafish to model various aspects of …

Comparative analyses of zebrafish anxiety-like behavior using conflict-based novelty tests

EV Kysil, DA Meshalkina, EE Frick, DJ Echevarria… - Zebrafish, 2017 - liebertpub.com
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in
neuroscience research and central nervous system (CNS) drug discovery. Representing the …

[HTML][HTML] Three-dimensional neurophenotyping of adult zebrafish behavior

J Cachat, A Stewart, E Utterback, P Hart, S Gaikwad… - PloS one, 2011 - journals.plos.org
The use of adult zebrafish (Danio rerio) in neurobehavioral research is rapidly expanding.
The present large-scale study applied the newest video-tracking and data-mining …