Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …

Background High-risk localised prostate cancer (HRCaP) has high rates of biochemical
recurrence;[177 Lu] Lu-PSMA-617 is effective in men with advanced prostate cancer …

Simple Summary Several studies showed that oxidative stress is involved in cancer
occurrence, development, progression chemoresistance and radio resistance. The nuclear …

Radiotherapy (RT) is a key treatment for prostate cancer. However, RT resistance can
contribute to treatment failure. Prostate cancer stem cells (PCSCs) are radioresistant. We …

225Ac-PSMA-617, targeting the prostate-specific membrane antigen (PSMA), which is
overexpressed on prostate cancer cells, has shown a remarkable therapeutic efficacy in …

Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

Aim To study the role of EGFR signaling in regulation of intrinsic resistance in prostate
cancer. Materials and methods Radioresistant prostate carcinoma DU145 and PC-3 cells …

Radiotherapy (RT) is a major modality for cancer treatment, along with surgery and
chemotherapy. Despite its therapeutic effect, the recurrence and metastasis of tumors due to …

Simple Summary Although epithelial-to-mesenchymal transition (EMT) is a well-known
cellular process involved during normal embryogenesis and wound healing, it also has a …