The use of animal models in biology research continues to be necessary for the
development of new technologies and medicines, and therefore crucial for enhancing …

Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Hundreds of human genes are associated with neurological diseases, but translation into
tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to …

CRISPR-Cas9 can be scaled up for large-scale screens in cultured cells, but CRISPR
screens in animals have been challenging because generating, validating, and keeping …

In the past few years, advances in machine learning have fueled an explosive growth of
descriptive and generative models of animal behavior. These new approaches offer higher …

Pharmacology and toxicology are part of a much broader effort to understand the
relationship between chemistry and biology. While biomedicine has necessarily focused on …

Collective behaviours, such as flocking in birds or decision making by bee colonies, are
some of the most intriguing behavioural phenomena in the animal kingdom. The study of …

Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …

Genetic engineering techniques have contributed to the now widespread use of zebrafish to
investigate gene function, but zebrafish-based human disease studies, and particularly for …

Complex schooling behaviors result from local interactions among individuals. Yet, how
sensory signals from neighbors are analyzed in the visuomotor stream of animals is poorly …