Nucleocytoplasmic transport: regulatory mechanisms and the implications in neurodegeneration

B Ding, M Sepehrimanesh - International journal of molecular sciences, 2021 - mdpi.com
Nucleocytoplasmic transport (NCT) across the nuclear envelope is precisely regulated in
eukaryotic cells, and it plays critical roles in maintenance of cellular homeostasis …

Into the basket and beyond: the journey of mRNA through the nuclear pore complex

A Ashkenazy-Titelman, Y Shav-Tal… - Biochemical …, 2020 - portlandpress.com
The genetic information encoded in nuclear mRNA destined to reach the cytoplasm requires
the interaction of the mRNA molecule with the nuclear pore complex (NPC) for the process …

[HTML][HTML] Prognostic risk signature based on the expression of three m6A RNA methylation regulatory genes in kidney renal papillary cell carcinoma

Z Sun, C Jing, C Xiao, T Li, Y Wang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
In this study, we investigated the prognostic significance of the expression of N6-
methyladenosine (m6A) RNA methylation regulatory genes in kidney renal papillary cell …

[HTML][HTML] Cryo-EM structure of the CBC-ALYREF complex

BP Clarke, AE Angelos, M Mei, PS Hill, Y Xie, Y Ren - eLife, 2023 - elifesciences.org
In eukaryotes, RNAs transcribed by RNA Pol II are modified at the 5'end with a 7-
methylguanosine (m7G) cap, which is recognized by the nuclear cap binding complex …

Strength in diversity: nuclear export of viral RNAs

JP Gales, J Kubina, A Geldreich, M Dimitrova - Viruses, 2020 - mdpi.com
The nuclear export of cellular mRNAs is a complex process that requires the orchestrated
participation of many proteins that are recruited during the early steps of mRNA synthesis …

Nuclear mRNA maturation and mRNA export control: from trypanosomes to opisthokonts

S Kramer - Parasitology, 2021 - cambridge.org
The passage of mRNAs through the nuclear pores into the cytoplasm is essential in all
eukaryotes. For regulation, mRNA export is tightly connected to the full machinery of nuclear …

Biological roles of RNA m7G modification and its implications in cancer

X Zhang, WY Zhu, SY Shen, JH Shen, XD Chen - Biology Direct, 2023 - Springer
M7G modification, known as one of the common post-transcriptional modifications of RNA, is
present in many different types of RNAs. With the accurate identification of m7G …

The promiscuity of the SAGA complex subunits: Multifunctional or moonlighting proteins?

C Nuno-Cabanes, S Rodriguez-Navarro - Biochimica et Biophysica Acta …, 2021 - Elsevier
Gene expression, the decoding of DNA information into accessible instructions for protein
synthesis, is a complex process in which multiple steps, including transcription, mRNA …

Viral RNA capping: Mechanisms and antiviral therapy

S Chen, Z Jiang, Q Li, W Pan, Y Chen… - Journal of Medical …, 2024 - Wiley Online Library
RNA capping is an essential trigger for protein translation in eukaryotic cells. Many viruses
have evolved various strategies for initiating the translation of viral genes and generating …

A multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6

C Nuño-Cabanes, M Ugidos, S Tarazona… - Scientific data, 2020 - nature.com
Gene expression is a biological process regulated at different molecular levels, including
chromatin accessibility, transcription, and RNA maturation and transport. In addition, these …