The transforming growth factor-β (TGFβ) family are a large group of evolutionarily conserved
cytokines whose signalling modulates cell fate decision-making across varying cellular …

Pulmonary arterial hypertension forms the first and most severe of the 5 categories of
pulmonary hypertension. Disease pathogenesis is driven by progressive remodeling of …

Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition
characterised by increased pulmonary arterial pressure, structural changes in the pulmonary …

Respiratory diseases are the cause of millions of deaths annually around the world. Despite
the recent growth of our understanding of underlying mechanisms contributing to the …

Pulmonary arterial hypertension (PAH) is a rare disease associated with abnormally
elevated pulmonary pressures and right heart failure resulting in high morbidity and …

Pulmonary arterial hypertension (PAH) is a rare disease characterized by high blood
pressure in the pulmonary circulation driven by pathological remodeling of distal pulmonary …

Bone morphogenetic proteins (BMPs) are secretory proteins belonging to the transforming
growth factor-β (TGF-β) superfamily. These proteins play important roles in embryogenesis …

Accurate phenotyping of patients with pulmonary hypertension (PH) is an integral part of
informing disease classification, treatment, and prognosis. The impact of lung disease on PH …

Pulmonary arterial hypertension (PAH) is a severe condition with a high mortality rate
despite advances in diagnostic and therapeutic strategies. In recent years, significant …

Pulmonary arterial hypertension (PAH) is a vascular remodeling disease, characterized by
increased blood pressure levels in pulmonary circulation, leading to a restriction in the …