Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview
D Kattan, C Barsa, S Mekhijian, Z Shakkour… - Neuroscience & …, 2023 - Elsevier
Given the ambiguity surrounding traumatic brain injury (TBI) pathophysiology and the lack of
any Food and Drug Administration (FDA)-approved neurotherapeutic drugs, there is an …
any Food and Drug Administration (FDA)-approved neurotherapeutic drugs, there is an …
[HTML][HTML] Increased risk of aging-related neurodegenerative disease after traumatic brain injury
Traumatic brain injury (TBI) survivors frequently suffer from chronically progressive
complications, including significantly increased risk of developing aging-related …
complications, including significantly increased risk of developing aging-related …
β-Amyloid and tau imaging in chronic traumatic brain injury: a cross-sectional study
Background and Objectives Traumatic brain injury (TBI) has been promoted as a risk factor
for Alzheimer disease (AD). There is evidence of elevated β-amyloid (Aβ) and tau, the …
for Alzheimer disease (AD). There is evidence of elevated β-amyloid (Aβ) and tau, the …
[HTML][HTML] Traumatic brain injury augurs ill for prolonged deficits in the brain's structural and functional integrity following controlled cortical impact injury
Previous neuroimaging studies in rodents investigated effects of the controlled cortical
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …
Brain age estimation reveals older adults' accelerated senescence after traumatic brain injury
Adults aged 60 and over are most vulnerable to mild traumatic brain injury (mTBI).
Nevertheless, the extent to which chronological age (CA) at injury affects TBI-related brain …
Nevertheless, the extent to which chronological age (CA) at injury affects TBI-related brain …
[HTML][HTML] The labyrinthine landscape of APP processing: state of the art and possible novel soluble APP-related molecular players in traumatic brain injury and …
Amyloid Precursor Protein (APP) and its cleavage processes have been widely investigated
in the past, in particular in the context of Alzheimer's Disease (AD). Evidence of an increased …
in the past, in particular in the context of Alzheimer's Disease (AD). Evidence of an increased …
Traumatic microRNAs: deconvolving the signal after severe traumatic brain injury
M Cente, K Matyasova, N Csicsatkova… - Cellular and Molecular …, 2023 - Springer
History of traumatic brain injury (TBI) represents a significant risk factor for development of
dementia and neurodegenerative disorders in later life. While histopathological sequelae …
dementia and neurodegenerative disorders in later life. While histopathological sequelae …
In pursuit of degenerative brain disease diagnosis: Dementia biomarkers detected by DNA aptamer-attached portable graphene biosensor
TA Bodily, A Ramanathan, S Wei… - Proceedings of the …, 2023 - National Acad Sciences
Dementia is a brain disease which results in irreversible and progressive loss of cognition
and motor activity. Despite global efforts, there is no simple and reliable diagnosis or …
and motor activity. Despite global efforts, there is no simple and reliable diagnosis or …
[HTML][HTML] Escalation of tau accumulation after a traumatic brain injury: findings from positron emission tomography
Traumatic brain injury (TBI) has come to be recognized as a risk factor for Alzheimer's
disease (AD), with poorly understood underlying mechanisms. We hypothesized that a …
disease (AD), with poorly understood underlying mechanisms. We hypothesized that a …
Differences in Risk of Alzheimer's Disease Following Later-Life Traumatic Brain Injury in Veteran and Civilian Populations
AP Yashkin, GA Gorbunova, L Tupler… - The Journal of Head …, 2023 - journals.lww.com
Objective: To directly compare the effect of incident age 68+ traumatic brain injury (TBI) on
the risk of diagnosis of clinical Alzheimer's disease (AD) in the general population of older …
the risk of diagnosis of clinical Alzheimer's disease (AD) in the general population of older …