Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …

This review aims to elucidate the different mechanisms of blood brain barrier (BBB)
disruption that may occur due to invasion by different types of bacteria, as well as to show …

Background Streptococcus pneumoniae meningitis is a serious inflammatory disease of the
central nervous system (CNS) and is associated with high morbidity and mortality rates. The …

Normal brain function is highly dependent on oxygen and nutrient supply and when the
demand for oxygen exceeds its supply, hypoxia is induced. Acute episodes of hypoxia may …

Prickly Ash Seeds (PAS), as a traditional Chinese medicinal herb, have pharmacological
effects such as anti-asthma, anti-thrombotic, and anti-bacterial, but their impact on gut …

Abstract Type 2 diabetes (T2D) is associated with accelerated cognitive decline. To date,
there is no T2D-specific treatment to prevent or ameliorate cognitive dysfunction. Boswellia …

Klebsiella pneumoniae is the most common pathogen of community-acquired meningitis in
Taiwan. However, the lack of a physiologically relevant meningitis model for K. pneumoniae …

Streptococcus pneumoniae is a major meningitis-causing pathogen globally, bringing about
significant morbidity and mortality, as well as long-term neurological sequelae in almost half …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative illnesses, and yet,
no workable treatments have been discovered to prevent or reverse AD. Curcumin (CUR) …