[HTML][HTML] Enhancing the sensitization of neuroblastoma to radiotherapy by the construction of a dual-channel parallel free radicals nanoamplifier

W Zhang, X Li, J Zeng, X Wen, C Zhang, Y Zhang… - Materials Today Bio, 2023 - Elsevier
Radiation therapy (RT) has emerged as one of the most promising anti-tumor strategies for
neuroblastoma. Nevertheless, the special tumor microenvironment (TME), including hypoxic …

[HTML][HTML] Nanoparticles (NPs)-mediated targeted regulation of redox homeostasis for effective cancer therapy

Z Zhao, Y Cao, R Xu, J Fang, Y Zhang, X Xu… - Smart Materials in …, 2024 - Elsevier
Although characterized by high reactive oxygen species (ROS) generation, cancer cells
maintain redox homeostasis to avoid severe damage (eg, DNA, protein, and plasma …

Nanoenabled tumor oxygenation strategies for overcoming Hypoxia-Associated immunosuppression

C Zhang, Q Yan, J Li, Y Zhu, Y Zhang - ACS Applied Bio Materials, 2020 - ACS Publications
Cancer immunotherapy, which initiates or strengthens innate immune responses to attack
cancer cells, has shown great promise in cancer treatment. However, low immune response …

Promotion of ICD via Nanotechnology

Y Qin, H Zhang, Y Li, T Xie, S Yan… - Macromolecular …, 2023 - Wiley Online Library
Immunotherapy represents the most promising treatment strategy for cancer, but suffers from
compromised therapeutic efficiency due to low immune activity of tumor cells and an …

Multi-faced roles of reactive oxygen species in anti-tumor T cell immune responses and combination immunotherapy

T Wang, H Xu - Exploration of Medicine, 2022 - explorationpub.com
T cells play a central role in anti-tumor immunity, and reactive oxygen species (ROS) lie at
the crossroad on the anti-tumor T cell responses. To activate efficient T cell immunity, a …

[HTML][HTML] Engineering nanomedicines for immunogenic eradication of cancer cells: Recent trends and synergistic approaches

AO Elzoghby, O Samir, HE Emam, A Soliman… - … Pharmaceutica Sinica B, 2024 - Elsevier
Resistance to cancer immunotherapy is mainly attributed to poor tumor immunogenicity as
well as the immunosuppressive tumor microenvironment (TME) leading to failure of immune …

Engineering Platelet Membrane Imitating Nanoparticles for Targeted Therapeutic Delivery

SB Adhalrao, KR Jadhav, PL Patil… - Current …, 2024 - ingentaconnect.com
Platelet Membrane Imitating Nanoparticles (PMINs) is a novel drug delivery system that
imitates the structure and functionality of platelet membranes. PMINs imitate surface markers …

[HTML][HTML] Iodine-Rich Nanoadjuvants for CT Imaging–Guided Photodynamic Immunotherapy of Breast Cancer

X Xin, X Ni, K Shi, J Shao, Y Zhang, X Peng… - … in Bioengineering and …, 2022 - frontiersin.org
Immunotherapy which stimulates body's own immune system to kill cancer cells has shown
great promise in the field of cancer therapy. However, the uncontrolled biodistribution of …

[HTML][HTML] 基于肿瘤乏氧增效光动力治疗的研究进展

尹小杰, 王晓倩, 张凤玲 - 药学学报, 2020 - html.rhhz.net
光动力治疗(PDT) 由于其微创, 高效和较高的选择性, 且能够诱导抗肿瘤免疫响应等独特的优点
而受到广泛关注. 但其治疗过程严重依赖于治疗部位的氧含量, 而恶性肿瘤中广泛存在乏氧现象 …

[HTML][HTML] 基于血小板的肿瘤靶向治疗策略与反思

赖晓雪, 王硕, 闫鑫杨, 刘欣荣, 宋艳志, 邓意辉 - 药学学报, 2020 - html.rhhz.net
在过去的几十年里, 对血小板的认识有了长足的进步, 血小板在癌症中发挥着意想不到的中心
作用, 极大地影响癌细胞的行为, 同时血小板的生理和表型也受到癌细胞的影响. 因此 …