[HTML][HTML] Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to …

JM Oh, BC Ahn - Theranostics, 2021 - ncbi.nlm.nih.gov
The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …

Thyroid cancer gender disparity

R Rahbari, L Zhang, E Kebebew - Future Oncology, 2010 - Taylor & Francis
Cancer gender disparity in incidence, disease aggressiveness and prognosis has been
observed in a variety of cancers. Thyroid cancer is one of the fastest growing cancer …

Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid Cancers

LA Dunn, EJ Sherman, SS Baxi… - The Journal of …, 2019 - academic.oup.com
Context BRAFV600E mutant thyroid cancers are often refractory to radioiodine (RAI).
Objectives To investigate the utility and molecular underpinnings of enhancing lesional …

The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta‐analysis

TH Kim, YJ Park, JA Lim, HY Ahn, EK Lee, YJ Lee… - Cancer, 2012 - Wiley Online Library
BACKGROUND: The effects of the BRAFV600E mutation on prognostic factors and poor
clinical outcomes in papillary thyroid cancer (PTC) have not been fully quantified. The …

BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

The association between papillary thyroid carcinoma and histologically proven Hashimoto's thyroiditis: a meta-analysis

JH Lee, Y Kim, JW Choi, YS Kim - European journal of …, 2013 - academic.oup.com
Objective No consensus exists on the association between papillary thyroid carcinoma
(PTC) and Hashimoto's thyroiditis (HT). To resolve this controversy, this study aimed to …

[HTML][HTML] Papillary thyroid cancer: genetic alterations and molecular biomarker investigations

MI Abdullah, SM Junit, KL Ng… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of
the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is …

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
Clinicians have long sought to characterize biological markers of neoplasia as objective
indicators of tumor presence, pathogenicity, and prognosis. Armed with data that correlate …

Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta‐analysis

JH Lee, JW Choi, YS Kim - British Journal of Dermatology, 2011 - academic.oup.com
Background There have been conflicting data regarding the prevalence and
clinicopathological characteristics of BRAF and NRAS mutations in primary cutaneous …

BRAFV600E Mutation and Outcome of Patients with Papillary Thyroid Carcinoma: A 15-Year Median Follow-Up Study

R Elisei, C Ugolini, D Viola, C Lupi… - The Journal of …, 2008 - academic.oup.com
Background: The BRAFV600E mutation is the most frequent genetic alteration in papillary
thyroid carcinoma (PTC). The role of BRAFV600E mutation as a poor prognostic factor has …