The cyclic adenosine monophosphate (cAMP) signaling pathway plays pleiotropic roles in
regulating development and pathogenicity in eukaryotes. cAMP is a second messenger that …

Fungal pathogens pose serious threats to human, plant, and ecosystem health. Improved
diagnostics and antifungal strategies are therefore urgently required. Here, we review recent …

Magnaporthe oryzae and Ustilaginoidea virens are two filamentous fungal pathogens that
threaten rice production worldwide. Genetic tools that permit fast gene deletion and …

The CRISPR-Cas9 system has a potential for wide application in organisms that particularly
present low homologous integration rates. In this study, we developed three different …

Acremonium chrysogenum is an important filamentous fungus which produces
cephalosporin C in industry. This review summarized the study on genetic engineering of …

Penicillium digitatum and Penicillium expansum are plant pathogenic fungi that cause the
green and blue mold diseases, respectively, leading to serious postharvest economic losses …

The latest breakthrough towards the adequate and decisive methods of gene editing tools
provided by CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic …

Abstract Objective To simplify CRISPR/Cas9 genome editing in the industrial filamentous
fungus Trichoderma reesei based on in vivo guide RNA (gRNA) transcription. Results Two …

The revolutionary discovery of penicillin only marks the start of our exploration for valuable
fungal natural products. Advanced genome sequencing technologies have translated the …

Blackleg, caused by the fungal pathogen Leptosphaeria maculans, is the most important
disease affecting canola (Brassica napus) crops worldwide. We employed the clustered …