Introduction: During the past few years, medical–economic evaluation of lung cancers (LCs)
has become unavoidable. Total management costs have been rising constantly, with values …

In our previous work, PC-9-Br, a PC-9 brain seeking line established via a preclinical animal
model of lung cancer brain metastasis (LCBM), exhibited not only resistance to epidermal …

Selenium (Se) and fish oil (FO) exert anti-epidermal growth factor receptor (EGFR) action on
tumors. This study aimed to compare the anti-cancer efficacy of EGFR inhibitors (gefitinib …

What is known and objective? Leptomeningeal metastasis (LM) is a serious complication of
advanced non‐small cell lung cancer (NSCLC) that is diagnosed in approximately 3%‐5 …

Background The efficacy and safety of combining epidermal growth factor receptor tyrosine
kinase inhibitors (EGFR-TKIs) with whole-brain radiotherapy (WBRT) for treating brain …

Treatment options for patients who develop brain metastases secondary to non-small-cell
lung cancer have rapidly expanded in recent years. As a key adjunct to surgical and …

Many in vitro and in vivo models are used in pharmacological research to evaluate the role
of targeted proteins in a disease. Understanding the translational relevance and limitation of …

Abstract Ethnopharmacological relevance The Chinese herbal medicine Fuzheng Kang-Ai
(FZKA) decoction obtained from Guangdong Kangmei Pharmaceutical Company, which …

The most commonly diagnosed malignancy of the urinary system is represented by renal
cell carcinoma. Various subvariants of RCC were described, with a clear-cell type prevailing …

The presence of an epidermal growth factor receptor (EGFR) mutation is associated with
higher incidence of brain metastases in patients with non-small cell lung cancer (NSCLC); …