The etiopathogenesis of inflammatory and autoimmune diseases, including pulmonary
disease, atherosclerosis, and rheumatoid arthritis, has been linked to human exposure to …

In our continuing examination of the role of exposomes in autoimmune disease, we use this
review to focus on pathogens. Infections are major contributors to the pathophysiology of …

Microbial transglutaminase (mTG) is a bacterial survival factor, frequently used as a food
additive to glue processed nutrients. As a result, new immunogenic epitopes are generated …

The use of innovative approaches to elucidate the pathophysiological mechanisms of
autoimmune diseases, as well as to further study of the factors which can have either a …

The CNS is very susceptible to oxidative stress; the gut microbiota plays an important role as
a trigger of oxidative damage that promotes mitochondrial dysfunction, neuroinflammation …

Toxic compounds can induce the formation of free radicals (reactive oxygen species (ROS))
which can trigger damage and decrease cell viability. Clove (Syzygium aromaticum) …

The gastrointestinal tract can be heavily infected by SARS-CoV-2. Being an auto-
immunogenic virus, SARS-CoV-2 represents an environmental factor that might play a role …

Systemic autoimmune diseases are complex conditions characterized by an immune system
dysregulation and an aberrant activation against self-antigens, leading to tissue and organ …

Immune checkpoint inhibitors herald a new era in oncological therapy-resistant cancer, thus
bringing hope for better outcomes and quality of life for patients. However, as with other …

The exposome encompasses all endogenous and exogenous exposure individuals
encounter throughout their lives, including biological, chemical, physical, psychological …