Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …

Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …

Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

Background Head and neck squamous cell carcinoma (HNSCC) is the most common head
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …

The core function of a multidisciplinary team (MDT) is to bring together a group of healthcare
professionals from different fields in order to determine patients' treatment plan. Most of head …

Three randomized phase III trials have now conclusively proven that exposure to a PD-1
inhibitor prolongs survival in recurrent/metastatic (R/M) HNSCC, and it is clear that such …

Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

Squamous cell carcinoma arises from multiple anatomic subsites in the head and neck
region. The risk factors for development of cancers of the oral cavity, oropharynx …

Background Cisplatin resistance is a major challenge for advanced head and neck cancer
(HNC). Understanding the underlying mechanisms and developing effective strategies …

Because a host's immune system is affected by host–microbiota interactions, means of
modulating the microbiota could be leveraged to augment the effectiveness of cancer …