Challenges in Optimizing Nanoplatforms Used for Local and Systemic Delivery in the Oral Cavity

DI Cocoș, O Dumitriu Buzia, AL Tatu, M Dinu… - Pharmaceutics, 2024 - mdpi.com
In this study, we focused on innovative approaches to improve drug administration in oral
pathology, especially by transmucosal and transdermal pathways. These improvements …

MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer

R Dinami, L Pompili, E Petti, M Porru… - EMBO Molecular …, 2023 - embopress.org
The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key
role in the maintenance of telomere structure and function. It is highly expressed in different …

Unlocking new dimensions in rheumatoid arthritis therapy: Harnessing the power of lipid based vesicles beyond traditional therapies

R Bahuguna, R Awasthi - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Rheumatoid arthritis (RA) is a persistent and chronic joint disease characterized by the
formation of autoantibodies that develop a local immune response at the synovial …

Controlled production of liposomes with novel microfluidic membrane emulsification for application of entrapping hydrophilic and lipophilic drugs

L Zhang, H Zhu, P Ye, L Zhu, Y Ren, J Lei - Journal of Industrial and …, 2024 - Elsevier
In view of the limitations in the reported methods for the preparation of liposomes, a new
microfluidic membrane emulsification device was innovatively designed and fabricated to …

[HTML][HTML] Solid lipid nanoparticles

TTL Nguyen, VA Duong - Encyclopedia, 2022 - mdpi.com
Definition Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible
lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce …

[HTML][HTML] Current status of immunological therapies for rheumatoid arthritis with a focus on antigen-specific therapeutic vaccines

DH Zimmerman, Z Szekanecz, A Markovics… - Frontiers in …, 2024 - frontiersin.org
Rheumatoid arthritis (RA) is recognized as an autoimmune joint disease driven by T cell
responses to self (or modified self or microbial mimic) antigens that trigger and aggravate …

[HTML][HTML] Lipid nano-system based topical drug delivery for management of rheumatoid arthritis: an overview

KD Dhule, TD Nandgude - Advanced Pharmaceutical Bulletin, 2023 - ncbi.nlm.nih.gov
The overall purpose of rheumatoid arthritis (RA) treatment is to give symptomatic alleviation;
there is no recognized cure for RA. Frequent use of potent drugs like non-steroidal anti …

Programmable Bionanomaterials for revolutionizing cancer immunotherapy

A Sharma, DD Bhatia - Biomaterials Science, 2024 - pubs.rsc.org
Cancer immunotherapy involves a cutting-edge method that utilizes the immune system to
detect and eliminate cancer cells. It has shown substantial effectiveness in treating different …

[HTML][HTML] Comparative In Vitro Study between Biocompatible Chitosan-Based Magnetic Nanocapsules and Liposome Formulations with Potential Application in Anti …

G Vochița, AN Cadinoiu, DM Rață… - International Journal of …, 2024 - mdpi.com
This study describes the comparison between the interaction of a series of peptide-
functionalized chitosan-based nanocapsules and liposomes with two cell lines, ie, mouse …

Current strategies and potential prospects for nanoparticle-mediated treatment of diabetic nephropathy

C Liu, K Wu, H Gao, J Li, X Xu - Diabetes, Metabolic Syndrome …, 2022 - Taylor & Francis
Diabetic nephropathy (DN), a severe microvascular complication of diabetes mellitus (DM),
is the most common form of chronic kidney disease (CKD) and a leading cause of renal …